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Specifications
- Antibody type:Primary
- Antigen name:Zinc Finger Protein, FOG family member 1
- Clonality:Polyclonal
- Gene ID:161882
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:ZFPM1
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:ZNF408,FOG1,ZC2HC11A,FOG,ZNF89A
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10490-066
Specifications
About this item
Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.
Recommended Dilutions: IHC-P: 1:100-500; IF(IHC-P): 1:50-200
Type: Primary
Antigen: ZFPM1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat