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- Antibody type:Primary
- Antigen name:SHC-transforming Protein 1
- Antigen symbol:SHC1
- Clonality:Polyclonal
- Conjugation:HRP (Horseradish Peroxidase)
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Gene ID:6464
- Antigen synonyms:SHC|SH2 domain protein C1|FLJ26504|SHC1|p66SHC|Src homology 2 domain-containing-transforming protein C1|SHC-transforming protein 1|p52SHC|p66|SHCA
- Modification:phospho-Tyr427
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10368-716
- Supplier No.:BS-3412R-HRP
The SHC gene encodes for a signaling and transforming protein containing Src homology 2 and 3 (SH2 and SH3) domains. The SHC gene encodes 2 widely expressed overlapping proteins of 46 and 52 kD, both containing a C-terminal SH2 domain. Adjacent to the SH2 region is a glycine and proline rich region. These 2 proteins differ in their N terminals. SHC proteins are involved in mitogenic signal transduction and act by coupling growth factor receptors to the RAS signaling pathway. The protein encoded by the SHC1 gene is thought to act as an adaptor in many signal transduction pathways.
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500
Type: Primary
Antigen: SHC1
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat