You searched for: Antibodies

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Rabbit polyclonal antibody to ALDOC for IHC and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to Smad3 for WB and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to RRAGC for WB and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to STMN3 for WB and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to NEGR1 for WB and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to CPE for WB and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to KCNG3 for WB and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to CDCP1 for WB and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to Cytochrome P450 21A2 for WB and ELISA with samples derived from Human.

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Rabbit polyclonal antibody to BRMS1 for WB and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to UNG for WB and ELISA with samples derived from Human, Mouse and Rat.

Supplier: Bioss

PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.

Supplier: Bioss

XAGE2 belongs to the GAGE family of genes which are expressed in a variety of tumors and in some fetal and reproductive tissues. XAGE2 is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. Its function is unknown.

Supplier: Bioss

Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.

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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq, Jul 2008].

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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq, Jul 2008].

Supplier: Bioss

PLEKHM3 (pleckstrin homology domain containing, family M, member 3), also known as DAPR or PLEKHM1L (pleckstrin homology domain containing, family M, member 1-like), is a 761 amino acid phosphoprotein that contains two pleckstrin homology (PH) domains and one phorbol-ester/DAG-type zinc finger. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PLEKHM3 exists as three alternatively spliced isoforms that participate in metal ion binding. The gene that encodes PLEKHM3 maps to human chromosome 2q33.3. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. Chromosome 2 contains a probable vestigial second centromere, as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

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Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

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Rabbit polyclonal antibody to Collagen V alpha3 for IHC, IF and ELISA with samples derived from Human.

Supplier: Biotium

CD45 / LCA Monoclonal antibody, Clone: 2B11 + PD7/26, Host: Mouse, Species reactivity: Human, Dog, Isotype: IgG's, Conjugate: purified, Immunogen: Isolated neoplastic cells from T cell lymphoma, Synonyms: B220, CD45R, Application: IF, Size: 100uL

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Goat polyclonal antibody to ABHD14B for ELISA and WB with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to AS250 for WB, IHC and ELISA with samples derived from Human and Mouse.

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Rabbit polyclonal antibody to SLC24A4 for WB and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to CD31 for Flow Cytometry, WB and IHC-P with samples derived from Human.

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Rabbit polyclonal antibody to TBX18 for WB and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to GATA4 for WB, IF and ELISA with samples derived from Human, Mouse and Rat.

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Rabbit polyclonal antibody to CIDEB for WB, IHC, IF and ELISA with samples derived from Human and Mouse.

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Goat polyclonal antibody to HOXD13 for ELISA, WB, IF and IHC with samples derived from Human and Rat.

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Rabbit polyclonal antibody to HDAC6 for WB, IHC, IF and ELISA with samples derived from Human and Mouse.

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Rabbit polyclonal antibody to BCAS2 for WB and ELISA with samples derived from Human, Mouse and Rat.