Human Recombinant Leptin (from E. coli)

Human Recombinant Leptin (from <i>E. coli</i>)

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.

Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.

A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.

: Ships at room temperature; Store at 20°C upon delivery.

Literature reference - PubMed ID 25917638

Shenandoah_Biotechnology_Product_Catalog

Catalog No:
10787-560
10787-562
10821-840

Protein/peptide name:
Leptin
Leptin
Leptin

Protein synonyms:
Obesity protein
Obesity protein
Obesity protein

Protein/peptide type:
Recombinant
Recombinant
Recombinant

Protein Function:
Cytokine
Cytokine
Cytokine

Species:
Human
Human
Human

Source:
E. coli
E. coli
E. coli

Conjugation:
Unconjugated
Unconjugated
Unconjugated

Gene ID:
Q6NT58
Q6NT58
Q6NT58

Sequence:
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC

Protease-free:
N
N
N

Animal-free:
N
N
N

Nuclease-free:
N
N
N

Carrier-free:
Y
Y
Y

Endotoxin-free:
N
N
N

Endotoxin level:
Low
Low
Low

Endotoxin content:
Endotoxin LAL (EU/µg) ≤1
Endotoxin LAL (EU/µg) ≤1
Endotoxin LAL (EU/µg) ≤1

Biological activity:
Bioactivity: No biological activity data is available at this time
Bioactivity: No biological activity data is available at this time
Bioactivity: No biological activity data is available at this time

Purity:
≥95%
≥95%
≥95%

Grade:
RUO
RUO
RUO

Formulation:
0.1% Trifluoroacetic Acid (TFA)
0.1% Trifluoroacetic Acid (TFA)
0.1% Trifluoroacetic Acid (TFA)

Molecular weight:
16.2 kDa
16.2 kDa
16.2 kDa

Reconstitution instructions:
Sterile water at 0.1 mg/ml
Sterile water at 0.1 mg/ml
Sterile water at 0.1 mg/ml

Storage conditions:
–20 °C
–20 °C
–20 °C

Shipping temperature:
RT
RT
RT

Product Family Options

Pack type
Size
Origin
10787-560
Vial
200 µg
US

Each (200µG)
Each (200µG) - $146.49
$146.49
Each (200µG)
$146.49

: 100-37-200UG

Specifications
Cat. No.
10787-560
Protein/peptide name
Leptin
Protein synonyms
Obesity protein
Protein/peptide type
Recombinant
Protein Function
Cytokine
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
Q6NT58
Sequence
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC
Protease-free
N
Animal-free
N
Nuclease-free
N
Carrier-free
Y
Endotoxin-free
N
Endotoxin level
Low
Endotoxin content
Endotoxin LAL (EU/µg) ≤1
Biological activity
Bioactivity: No biological activity data is available at this time
Purity
≥95%
Grade
RUO
Formulation
0.1% Trifluoroacetic Acid (TFA)
Molecular weight
16.2 kDa
Reconstitution instructions
Sterile water at 0.1 mg/ml
Storage conditions
–20 °C
Shipping temperature
RT
10787-562
Vial
5 mg
US

Each (5mg)
Each (5mg) - $537.45
$537.45
Each (5mg)
$537.45

: 100-37-5MG

Specifications
Cat. No.
10787-562
Protein/peptide name
Leptin
Protein synonyms
Obesity protein
Protein/peptide type
Recombinant
Protein Function
Cytokine
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
Q6NT58
Sequence
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC
Protease-free
N
Animal-free
N
Nuclease-free
N
Carrier-free
Y
Endotoxin-free
N
Endotoxin level
Low
Endotoxin content
Endotoxin LAL (EU/µg) ≤1
Biological activity
Bioactivity: No biological activity data is available at this time
Purity
≥95%
Grade
RUO
Formulation
0.1% Trifluoroacetic Acid (TFA)
Molecular weight
16.2 kDa
Reconstitution instructions
Sterile water at 0.1 mg/ml
Storage conditions
–20 °C
Shipping temperature
RT
10821-840
Vial
10 mg

Each (10mg)
Each (10mg) - $936.74
$936.74
Each (10mg)
$936.74

: 100-37-10MG

Specifications
Cat. No.
10821-840
Protein/peptide name
Leptin
Protein synonyms
Obesity protein
Protein/peptide type
Recombinant
Protein Function
Cytokine
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
Q6NT58
Sequence
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC
Protease-free
N
Animal-free
N
Nuclease-free
N
Carrier-free
Y
Endotoxin-free
N
Endotoxin level
Low
Endotoxin content
Endotoxin LAL (EU/µg) ≤1
Biological activity
Bioactivity: No biological activity data is available at this time
Purity
≥95%
Grade
RUO
Formulation
0.1% Trifluoroacetic Acid (TFA)
Molecular weight
16.2 kDa
Reconstitution instructions
Sterile water at 0.1 mg/ml
Storage conditions
–20 °C
Shipping temperature
RT