About this item
Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7,) or in combination of IL-7 and interleukin 3 (IL-3). Human FLT-3 ligand is active on mouse cells.
Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.
A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.
Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:–20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0.1
- Biological activity:Bioactivity assay: OCI-Aml5 cell proliferation, ED50 ≤5 ng/ml, Bioactivity ≥2.0×10⁵ units/mg
- Gene ID:P49771
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:N
- Protein synonyms:Flt3L|Fms-related tyrosine kinase 3 ligand
- Protein/peptide name:FLT-3 Ligand
- Purity:≥97%
- Molecular weight:17.7 kDa
- Sequence:MTQDCSFQHS PISSDFAVKI RELSDYLLQD YPVTVASNLQ DEELCGGLWR LVLAQRWMER LKTVAGSKMQ GLLERVNTEI HFVTKCAFQP PPSCLRFVQT NISRLLQETS EQLVALKPWI TRQNFSRCLE LQCQPDSSTL PPPWSPRPLE ATAPT
- Endotoxin level:Low
- Formulation:10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
- Nuclease-free:N
- Shipping temperature:RT
- Tested applications:Bioassay
- Grade:RUO
Specifications
Related Information
Certificates
Search by Lot NumberLiterature reference - PubMed ID 28211886 Literature reference - PubMed ID 29520027
Additional Product Details
Shenandoah_Biotechnology_Product_Catalog