Specifications
- Antibody type:Primary
- Antigen symbol:B23
- Clonality:Monoclonal
- Clone:4F12A3
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG1
- Reactivity:Human
- Western blot:Yes
- Size:150 µL
- Storage buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Caprylic Acid/Ammonium Sulfate Precipitation
- Cat. no.:10083-434
- Supplier No.:60096-1-IG
Specifications
About this item
Nucleophosmin (NPM1,B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs). The transport of proteins across the nuclear envelope is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. The 38 kDa nuclear protein nucleophosmin is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.
Western Blot: Hepg2 Cells, 1:500-1:5000; IHC: Human breast cancer Tissue, 1:20-1:200; IF: MCF-7 Cells, 1:10-1:100
Type: Primary
Antigen: B23
Clonality: Monoclonal
Clone: 4F12A3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human