Specifications
- Antibody type:Primary
- Antigen name:Protein Tyrosine Phosphatase, Non-receptor Type 11
- Antigen symbol:PTPN11
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Size:150 µL
- Antigen synonyms:SHP2|PTP2C|PTP-1D|SH-PTP3|METCDS|NS1|CFC|SH-PTP2|BPTP3|JMML
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Fusion Protein
- Purification:Antigen affinity Purification
- Cat. no.:10094-632
- Supplier No.:20145-1-AP
Specifications
About this item
PTPN11(protein tyrosine phosphatase, non-receptor type 11) is also named as PTP-1D, PTP2, PTP2C, PTP3, SHP2, CFC, CFC, BPTP3, SH-PTP2, SH-PTP3, MGC14433 and belongs to the protein-tyrosine phosphatase family and non-receptor class 2 subfamily. It modulates and regulates signaling through numerous pathways, many of which are active in the developing endocardial cushions and implicated the ERK pathway as a central mechanism. Its signaling may play equally important roles in retinal survival in both physiological and pathological conditions. Defects in PTPN11 are the cause of LEOPARD syndrome type 1 (LEOPARD1), Noonan syndrome type 1 (NS1), juvenile myelomonocytic leukemia (JMML) and metachondromatosis (MC). It has 3 isoforms produced by alternative splicing.
Western Blot:Jurkat Cells, 1:500-1:5000; IHC: Human breast cancer Tissue, 1:20-1:200; IF: Hela Cells, 1:10-1:100
Type: Primary
Antigen: PTPN11
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat