Specifications
- Antibody type:Primary
- Antigen name:Kirsten Rat Sarcoma Viral Oncogene
- Antigen symbol:KRAS
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Size:150 µL
- Antigen synonyms:KI-RAS|KRAS2|KRAS1|K-RAS2B|NS3|K-RAS4B|NS|RASK2|C-K-RAS|K-RAS4A|K-RAS2A|RALD|CFC2
- Storage buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. no.:10089-368
- Supplier No.:12063-1-AP
Specifications
About this item
KRAS, also called p21, is a member of the Ras superfamily of proteins. It is located on human chromosome 12, and contains four coding exons and a 5' non-coding exon . KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family, the KRAS protein is a GTPase, and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation . KRAS mutations have been found in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. KRAS has two isoforms, a and b. This KRAS antibody (12063-1-AP) is a Pan-RAS antibody.
Western Blot: Mouse Brain Tissue, 1:500-1:5000; IHC: Human Colon cancer Tissue, 1:20-1:200; IP: HeLa Cells, 1:500-1:5000; FC: HeLa Cells, N/A
Type: Primary
Antigen: KRAS
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat