Purospher® RP-18 is designed for the separation of problematic basic compounds with simple neutral eluents.

Purospher® RP-18e is a versatile high-purity HPLC column producing excellent peak shapes, designed for both the separation of basic compounds with simple neutral eluents and for the elution of strongly acidic compounds. Excellent separations in a shorter period of time with very good peak symmetry saves time and money. The excellent balance of Purospher® RP-18e in the sum of its chromatographic properties is the key to better separations of complex samples with simpler, neutral eluents. The good chemical stability of Purospher® RP-18e enables the use of mobile phase conditions at pH 8 for a long period of time.

In addition Purospher® RP-18 allows the separation of hydrophilic compounds with aqueous mobile phase. Purospher® RP-18 is based upon a high-purity, metal free silica. The multi-step chemical modification and deactivation of the surface and the polar endcapping enables a peak-tailing free elution of basic and chelating compounds. Purospher® RP-18 is not suitable for the separation of acidic compounds.