Human Recombinant SCF (from E. coli)

Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant rat SCF is an 18.4 kDa polypeptide containing 154 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF. Recombinant murine SCF is an 18.3 kDa polypeptide containing 164 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF. Recombinant human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

Store in working aliquots at -20°C. Avoid freeze/thaw cycles.

Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Biological activity:
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is = 2.0 ng/mL, corresponding to a specific activity of = 5 x 10⁵ units/mg.
Protein synonyms:
Kit ligand|SCF|KL-1|Kitl|SF|FPH2|Mast cell growth factor|MGF|SHEP7
Protein/peptide name:
SCF
Purity:
>98%
Formulation:
Lyophilized
Gene ID:
60427