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- Antibody type:Primary
- Antigen name:SUZ12 polycomb repressive complex 2 subunit
- Antigen symbol:SUZ12
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Size:0.1 mg
- Environmentally Preferable:
- Form:Liquid
- Gene ID:Q15022
- Antigen synonyms:SUZ12
- Storage buffer:SUZ12 antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Predicted: 81 kDa Observed: 96 kDa
- Storage temperature:SUZ12 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:SUZ12 antibody was raised against a 19 amino acid peptide near the center of human SUZ12. The immunogen is located within amino acids 400 - 450 of SUZ12.
- Purification:SUZ12 antibody is affinity chromatography purified via peptide column.
- Cat. no.:10062-584
- Supplier No.:7701
The Polycomb group (PcG) genes contribute to the maintenance of cell identity, cell cycle regulation and oncogenesis. SUZ12 (suppressor of zeste 12) is a 90 - 95 kDa member of the polycomb group of transcriptional regulators. It is part of a transcription repression complex termed PRC2 (Polycomb repressive complex 2) that methylates histones in the nucleus, resulting in homeotic (pattern-inducing) gene silencing. It contains one C2H2-type zinc finger region and a C-terminal VEFS-box. SUZ12 is overexpressed in breast and colon cancer. SUZ12 may be a cause of endometrial stromal tumors.
SUZ12 antibody can be used for detection of SUZ12 by Western blot at 1 - 2 ?g/ml. Antibody can also be used for Immunohistochemistry starting at 5 ?g/mL. For immunofluorescence start at 20 ?g/mL.
SUZ12 antibody is affinity chromatography purified via peptide column.
SUZ12 antibody is supplied in PBS containing 0.02% sodium azide.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: SUZ12
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human