You searched for: Antibodies

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Recombinant rabbit monoclonal [PDPN/7808R] antibody to Podoplanin / gp36 for ELISA, IF and IHC-P with samples derived from Human.

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Mouse monoclonal [66IG10] antibody to Transferrin Receptor for ELISA, Flow Cytometry and IF with samples derived from Human.

Supplier: Bioss

The synucleins, including Alpha-synuclein (also designated NACP for nonamyloid component precursor),Beta-synuclein (also designated PNP 14 for neuroprotein 14)and Gamma-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1)are presynaptic protein abundant in neurons. Alpha-synuclein, a component of Alzheimer’s disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of Alpha-synucleinand Beta-synuclein may be important during hematopoetic cell differentiation. In patients with Parkinson’s disease, a mutant form of Alpha-synuclein has been found and Gamma-synuclein is associated with axonal pathology.

Supplier: Bioss

Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Supplier: Bioss

This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Supplier: Bioss

This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

Supplier: Biotium

This antibody recognizes a protein of 55 kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

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Rabbit monoclonal [ARC54617] antibody to COMP/Cartilage oligomeric matrix protein for WB with samples derived from Human, Mouse and Rat.

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Rabbit monoclonal [ARC1545] antibody to CDK1 + CDK2 + CDK3 (phospho Thr14) for WB with samples derived from Human, Mouse and Rat.

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Mouse monoclonal [2G1] antibody to SARS-CoV-2 Spike Glycoprotein RBD for WB and ICC/IF with samples derived from SARS-CoV-2.

Supplier: Prosci

The ICRF44 monoclonal antibody specifically reacts with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin beta 2) a complex known as Mac-1. CD11b is expressed on the surface of activated lymphocytes, a subset of natural killer cells, granulocytes, and monocytes. It functions as a receptor in cell-cell and cell-matrix interactions and as a receptor for iC3b, ICAM-1, ICAM-2, and ICAM-3 intercellular adhesion molecules.

Supplier: Bioss

Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

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Mouse monoclonal [GP2/1805] antibody to Glycoprotein 2 for ELISA, WB and IHC-P with samples derived from Human.

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Mouse monoclonal [LPLUNC1/3206] antibody to L-PLUNC for ELISA, WB and IHC-P with samples derived from Human.

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Rabbit monoclonal [ARC2915] antibody to SLC12A1 / NKCC2 for WB with samples derived from Human, Mouse and Rat.

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Rabbit monoclonal [ARC57469] antibody to GDF8 / Myostatin for WB with samples derived from Human, Mouse and Rat.

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Rabbit monoclonal [ARC2136] antibody to PGC1 beta for WB with samples derived from Human, Mouse and Rat.

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Rabbit monoclonal [ARC0038] antibody to Caspase-6/CASP-6 for WB and ICC/IF with samples derived from Human and Mouse.

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Goat Anti-Mouse IgG H&L Antibody (TRITC) for ICC/IF and Flow Cytometry with samples derived from Mouse.

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Rabbit monoclonal [ARC1958] antibody to Mib1/Mindbomb for WB with samples derived from Human, Mouse and Rat.

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Rabbit monoclonal [ARC1650] antibody to alpha 1 Spectrin for WB with samples derived from Human, Mouse and Rat.

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Rabbit monoclonal [ARC0828] antibody to NOXA2/p67phox for WB and IHC with samples derived from Mouse and Rat.

Supplier: Prosci

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

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Mouse monoclonal [EGP40/1372] antibody to EpCAM for Flow Cytometry, IF, WB and IHC-P with samples derived from Human.

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Mouse monoclonal [EGP40/837] antibody to EpCAM for Flow Cytometry, IF, WB and IHC-P with samples derived from Human.

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Mouse monoclonal [PTPRC/1148] antibody to CD45RA for Flow Cytometry, WB, IF and IHC-P with samples derived from Human.

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Mouse monoclonal [PTPRC/1147] antibody to CD45RB for Flow Cytometry, IF, WB and IHC-P with samples derived from Human.

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Mouse monoclonal [BL10/411] antibody to BCL10 for Flow Cytometry, WB and IHC-P with samples derived from Human.

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Mouse monoclonal [LPSR/2385] antibody to CD14 for WB, Flow Cytometry and IHC-P with samples derived from Human.

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Mouse monoclonal [NT5E/2503] antibody to CD73 for WB, Flow Cytometry, IF and IHC-P with samples derived from Human.