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Anti-SLC35D1 Rabbit Polyclonal Antibody
Anti-SLC35D1 Rabbit Polyclonal Antibody
Catalog # 89416-622
Supplier:  Prosci
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Anti-SLC35D1 Rabbit Polyclonal Antibody
Catalog # 89416-622
Supplier:  Prosci
Supplier Number:  4649

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
  • Antigen symbol:
    SLC35D1
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Size:
    0.1 mg
  • Form:
    Liquid
  • Gene ID:
    Q9NTN3
  • Antigen synonyms:
    SLC35D1
  • Storage buffer:
    Slc35D1 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Storage temperature:
    Slc35D1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    1 mg/mL
  • Shipping temperature:
    4 °C
  • Immunogen:
    Slc35D1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of the human Slc35D1. The immunogen is located within the first 50 amino acids of Slc35D1.
  • Tested applications:
    E, WB
  • Purification:
    Slc35D1 Antibody is affinity chromatography purified via peptide column.
  • Cat. no.:
    89416-622
  • Supplier No.:
    4649

Specifications

About this item

Slc35D1 Antibody: The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident Slc family member Slc35D1 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. These molecules can serve as substrates for chondroitin sulfate biosynthesis and mice lacking the Slc35D1 gene developed a lethal form of skeletal dysplasia with severe shortening of limbs and facial structures. Examination of epiphyseal cartilage in these mice revealed a decreased proliferating zone with round chrondrocytes, scarce matrices, and reduced proteoglycan aggregates. Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia.

Type: Primary
Antigen: SLC35D1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat