T4 PDG (T4 Endonuclease V), New England Biolabs
Catalog # CA200064-436
Supplier: New England Biolabs (NEB)
CAS Number:
Specifications
- Size:2000 units
- Enzyme name:T4 PDG (T4 Endonuclease V)
- Cat. no.:CA200064-436
Specifications
About this item
T4 PDG (pyrimidine dimer glycosylase) has both DNA glycosylase and AP-lyase activity
The 16 kd protein recognizes cis-syn-cyclobutane pyrimidine dimers caused by UV irradiation. The enzyme cleaves the glycosyl bond of the 5´ end of the pyrimidine dimer and the endonucleolytic activity cleaves the phosphodiester bond at the apurinic/apyrimidinic (AP) site.