Fpg
About this item
Fpg (formamidopyrimidine [fapy]-DNA glycosylase), also known as 8-oxoguanine DNA glycosylase, acts both as an N-glycosylase and an AP-lyase
The N-glycosylase activity releases damaged purines from double-stranded DNA, generating an apurinic (AP) site. The AP-lyase activity cleaves both 3´ and 5´ to the AP site thereby removing the AP site and leaving a 1-base gap with a 5´ and 3´ phosphate. Some of the damaged bases recognized and removed by Fpg include 7, 8-dihydro-8-oxoguanine (8-oxoguanine), 8-oxoadenine, fapy-guanine, methy-fapy-guanine, fapy-adenine, aflatoxin B1-fapy-guanine, 5-hydroxy-cytosine and 5-hydroxy-uracil.
2 Options Available Below
Product Details & Documents
Fpg (formamidopyrimidine [fapy]-DNA glycosylase), also known as 8-oxoguanine DNA glycosylase, acts both as an N-glycosylase and an AP-lyase
The N-glycosylase activity releases damaged purines from double-stranded DNA, generating an apurinic (AP) site. The AP-lyase activity cleaves both 3´ and 5´ to the AP site thereby removing the AP site and leaving a 1-base gap with a 5´ and 3´ phosphate. Some of the damaged bases recognized and removed by Fpg include 7, 8-dihydro-8-oxoguanine (8-oxoguanine), 8-oxoadenine, fapy-guanine, methy-fapy-guanine, fapy-adenine, aflatoxin B1-fapy-guanine, 5-hydroxy-cytosine and 5-hydroxy-uracil.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- CA101227-630
- CA101227-628
- Enzyme name:
- Fpg
- Fpg
Specifications
Product Family Options
Product Information
- SizeAvailabilityPrice
- Supplier Number: M0240SSpecifications:
More
Specifications
Cat. No.CA101227-630Enzyme nameFpg - Supplier Number: M0240LSpecifications:
More
Specifications
Cat. No.CA101227-628Enzyme nameFpg
Recommendations will be personalized based on your shopping preferences only if you have given your consent by enabling "Enhance my Shopping Experience" on the "Personal Info page".
Otherwise, you will receive generic recommendations.
Catalog #: CA21905-026
Supplier: Kimberly-Clark