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Specifications
- Protein/peptide type:Recombinant
- Source:Insect cells (Sf9)
- Species:Human
- Size:50 µg
- Tag sequence:HIS Tag
- Biological activity:Hydrolysis of N-ε-acetyl-lysine residues of histones.
>3U/μg. One unit is defined as the amount of enzyme that deacetylates 1 pmol/min of Fluor de Lys™-SIRT1 (Prod. No. BML-KI177) substrate at 37°C / 500μM. - Protein/peptide name:HDAC11
- Purity:>50% (SDS-PAGE)
- Formulation:Liquid. In 50mM TRIS, pH 8.0, containing 138mM NaCl and 10% glycerol.
- Cat. no.:89164-534
- Supplier No.:SE560-0050
Specifications
About this item
Highly active
Produced in Sf9 cells. HDAC11 from human cDNA, transcript variant 1 (identical to GenBank accession NM_024827) is fused at the N-terminus to a His-tag.
Deacetylates lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.