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Specifications
- Protein/peptide type:Recombinant
- Species:Human
- Size:10 µg
- Tag sequence:HIS Tag
- Biological activity:436 U/µg protein. One unit will hydrolyze one pmole Z-Leu-Arg-AMC substrate (Prod. No. BML-P229, 25 µM) per minute at 25°C, in 25mM NaOAc pH 5.5, 100mM NaCl, 1.0mM DTT.
- Protein/peptide name:Procathepsin V
- Purity:>90%
- Formulation:Liquid. In 25mM TRIS-HCl, pH 8.0, containing 100mM sodium chloride, 0.05% Tween-20 and 10% glycerol.
- Cat. no.:89164-522
- Supplier No.:SE554-0010
Specifications
About this item
Produced in insect cells.
Recombinant glycosylated procathepsin V cloned from human cDNA and purified as full-length proenzyme. Can be activated in one step. Cathepsin V, a member of the papain family of cysteine proteases, has 78% identity to cathepsin L, but unlike cathepsin L is not widely expressed, being localized to thymus, testis, corneal epithelium, and macrophages. It is a strong elastase, also cleaving proteins such as the invariant chain (Ii), plasminogen, and kininogen. It is implicated in disease states such as cancer, angiogenesis, atherosclerosis, and myasthenia gravis.