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Human Neutrophil elastase (from Neutrophils)
Human Neutrophil elastase (from Neutrophils)
Catalog # 89163-944
Supplier:  Enzo Life Sciences
CAS Number:  
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Human Neutrophil elastase (from Neutrophils)
Catalog # 89163-944
Supplier:  Enzo Life Sciences
Supplier Number:  BML-SE284-0100
CAS Number:  

Specifications

  • Source:
    Neutrophils
  • Species:
    Human
  • Size:
    100 µg
  • Enzyme name:
    Neutrophil elastase
  • Enzyme activity:
    20 - 22 U/mg protein. One unit will hydrolyze 1.0 µmole of MeOSuc-Ala-Ala-Pro-Val-pNA (Prod. No. BML-P213) per minute, at 25 °C, pH 8.0.
  • Purity:
    >95% (SDS-PAGE). Although this is in highly purified form, and the source material tested negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2, handle this product with all due precautions.
  • Cat. no.:
    89163-944
  • Supplier No.:
    SE284-0100

Specifications

About this item

Isolated from human neutrophils. Active enzyme.

Functions in inflammation. Can cleave a variety of proteins, including fibrous elastin, collagen, clotting factors, TNF-α , and α 1- antichymotrypsin. Because of its potential roles in inflammatory diseases such as emphysema and cystic fibrosis, it is a target for drug discovery.