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Specifications
- Size:5 mg
- Protein/peptide name:RGD Peptide
- Purity:>97% (HPLC)
- Cat. no.:89161-294
- Supplier No.:P700-0005
Specifications
About this item
Integrin ligand
Induces apoptosis in various cell types and cell lines at 1mM by a mechanism involving cellular uptake and possible direct stimulation of procaspase-3 autoprocessing. Does not induce apoptosis in the breast cancer line MCF-7, in which there is a functional deletion of the procaspase-3 gene. Contains the motif RGD (Arg-Gly-Asp) which is found in many integrin ligands. Inhibits cell adhesion of COS-7 cells to fibronectin 80-90% at 1mM.