To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Specifications
- Protein/peptide type:Recombinant
- Size:100 µg
- Protein/peptide name:Charybdotoxin
- Purity:98%
- Cat. no.:89160-264
- Supplier No.:KC168-0100
Specifications
About this item
K+ channel blocker
Charybdotoxin was originally isolated from the venom of the Israeli scorpion Leiurus quinquestriatus hebraeus. Charybdotoxin blocks KCa1.1 (large conductance Ca2+ activated K+, Slo) channels in nanomolar concentrations as as well as Kv1.2 (Kd, 14 nM) and Kv1.3 (Kd, 2.6 nM) channels.). However, experiments with cloned KCa1.1 channels demonstrate the strong effect of the slob subunits on the potency of block by Charybdotoxin. This product is a recombinant peptide expressed in and extracted from E. coli.