Alpha-Dendrotoxin
Catalog #: 89160-262
Supplier: Enzo Life Sciences
CAS Number:
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Specifications
- Size:140 µg
- Protein/peptide name:alpha-Dendrotoxin
- Purity:>98% (HPLC)
- Cat. no.:89160-262
- Supplier No.:KC167-0140
Specifications
About this item
K+ channel blocker.
- alpha-Dendrotoxin is isolated from Dendroaspis angusticeps snake venom, by modification of the procedures of Harvey and Benishin and purified to homogeneity. α-Dendrotoxin blocks Kv1.1 and Kv1.2 channels (IC50= 0.4 to 4 and 1.1 to 12 nM in oocytes respectively, with higher values for mammalian cells). In addition, the toxin was shown to block also Kv1.6 (IC50= 9-25 nM).
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