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Specifications
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Size:100 µg
- Endotoxin content:\<1.0EU/µg of protein (LAL method).
- Protein/peptide name:alpha-Synuclein
- Purity:>95% (SDS-PAGE)
- Concentration:1mg/ml.
- Formulation:Liquid. In 20mM TRIS-HCl, pH 7.5, containing 0.1M sodium chloride and 1mM magnesium dichloride.
- Cat. no.:89144-392
- Supplier No.:201-265-C100
Specifications
About this item
Produced in E. coli.
alpha-synuclein is a major component of Parkinson's disease aggregates and is implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders. alpha-synuclein accumulates in the brains of sporadic Parkinson's disease patients as a major component of Lewy bodies, which are intraneuronal cytoplasmic inclusions characteristic of Parkinson's disease. alpha-synuclein appears to associate with other proteins that aggregate and is found in beta-amyloid plaques and neuritic tangles in Alzheinmer's disease.