Bovine;Guinea pig;Human;Mouse;Rat (Ser⁸)-GLP-1 (7-36) Amide Trifluoroacetate

For the long-acting GLP-1 analog liraglutide see H-6724.

The replacement of alanine by serine significantly improved the plasma stability of GLP-1 (7-36) amide against DPP IV without impairing its insulinotropic activity. This may indicate that this modification could improve the potential of GLP-1 in the treatment of type-II diabetes.

CAS No.:
215777-46-1
Species:
Human
Bovine
Guinea pig
Rat
Mouse
Storage conditions:
–20 ± 5 °C
MDL No.:
MFCD02266190
Protein synonyms:
(Ser8)-Glucagon-like Peptide 1 (7-36) amide|(Ser99)-Preproglucagon (98-127) amide|(Ser79)-Proglucagon (78-107) amide
Protein/peptide name:
(Ser⁸)-GLP-1 (7-36) amide Trifluoroacetate
Molecular weight:
3313.68
Sequence:
H-His-Ser-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH₂
Molecular formula:
C₁₄₉H₂₂₆N₄₀O₄₆