You searched for: Antibodies

Supplier: Rockland Immunochemical

This product has been assayed against 1.0 µg of Guinea pig IgG in a standard capture ELISA using pNPP p-nitrophenyl phosphate as a substrate for 30 minutes at room temperature.

Supplier: Immunoreagents

IgG (H&L) Antibody, Affinity Pure, Host: Goat, Species Reactivity: Mouse, Immunogen: Purified Mouse IgG, whole molecule, Conjugate: DyLight* 650, Concentration: 1.0 mg/ml, Form: Lyophilized, Applications: Immunomicroscopy and flow cytometry, Storage: 2-8 deg C

Supplier: Immunoreagents

IgG (H&L) Antibody, Affinity Pure, Host: Donkey, Species Reactivity: Sheep, Concentration: 10mg/ml, Conjugate: DyLight* 650, Form: Liquid, 0.2 um filtered, Purification: Affinity purified using solid phase biotin, Applications: Immunoassay, Storage: 2-8 deg C

Supplier: Immunoreagents

IgG (H&L) Antibody, Host: Llama, Species Reactivity: Mouse, Immunogen: Avian IgY, Conjugate: Horseradish Peroxidase, Concentration: 1.0 mg/ml, Form: Lyophilized, Affinity purified, Purity: > 95% based on SDS-PAGE, Applications: Immunomicroscopy, Storage: 2-8 deg C

Supplier: Tonbo Biosciences

Rabbit anti-Goat IgG (H&L) - Affinity Pure, HRP Conjugate

Supplier: Tonbo Biosciences

The L243 antibody reacts with a member of the human MHC Class II antigens, HLA-DR. The HLA-DR antigen is expressed on B lymphocytes, activated T lymphocytes, activated NK cells, monocytes, macrophages, other antigen presenting cells and progenitor cells. The L243 antibody is specific to an epitope on the alpha subunit of the heterodimeric HLA-DR protein and binds a different epitope than the LN3 antibody clone. It does not cross-react with HLA-DP or HLA-DQ. This antibody is reported to be cross-reactive with non-human primates including Chimpanzee, Cynomolgus, Rhesus and Baboon. Please choose the appropriate format for each application.

Supplier: Rockland Immunochemical

Anti-TRPM7 Antibody is suitable for use in WB, IP, and Immunofluorescence microscopy. Antibody is provided in PBS pH 7.4. Expect a band approximately ~220kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Supplier: Tonbo Biosciences

The UCHL1 antibody reacts with the human CD45 isoform known as CD45RO, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA and CD45RB. The UCHL1 antibody is widely used as a marker for human CD45RO expression on thymocytes, activated memory T cells, monocytes, macrophages and granulocytes. The antibody is reported to be cross-reactive for Chimpanzee CD45RO.

Supplier: Tonbo Biosciences

Rabbit anti-mouse IgG (H&L) - Affinity Pure, min x w/human serum proteins

Supplier: Rockland Immunochemical

Anti-IgM µ Goat Polyclonal Antibody (Texas Red®)

Supplier: Immunoreagents

Supplier: Rockland Immunochemical

Rockland produces a wide range of human GST antibodies in our laboratories. Select appropriate GST antibodies for your research by isotype, epitope, applications and species reactivity. There are 22 members of the human GST family of proteins. GST is responsible for the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. The amino acid sequence GST is highly conserved in most organisms including mammals. GSTs proteins are typically homodimeric, with both heterologous GST dimers have been observed. GST monomers have an average molecular weight of approximately 25-28 kDa in size. Note a different form of non-human GST (Glutathione-S-Transferase) is used as a protein expression tag commonly in molecular biology applications. All anti-GST antibodies my not react with recombinant GST-fusion proteins.

Supplier: Tonbo Biosciences

Goat anti-Rabbit IgG (H&L) - Affinity Pure, Biotin Conjugate

Supplier: Rockland Immunochemical

HbC antibodies detect the E6K mutant in the hemoglobin beta subunit. Functional hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 beta subunits (α2β2). Common isoform variants of hemoglobin include HbA, HbS, HbC, HbF, and HbA2. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Globin gene mutations affect the structure and expression levels of Hb. Sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. Less significant than the SCD-E6V, HbC E6K mutation causes a mild hemolytic anemia. HbC antibody does not react to other forms of Hb. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.

Supplier: Rockland Immunochemical

Anti luciferase Antibody recognizes luciferase that is commonly used in biological research as a reporter to assess the transcriptional activity in cells that are transfected with a genetic construct containing the luciferase gene under the control of a promoter of interest. Luciferase can also be used to detect the level of cellular ATP in cell viability assays or for kinase activity assays. Additionally proluminescent molecules that are converted to luciferin upon activity of a particular enzyme can be used to detect enzyme activity in coupled or two-step luciferase assays. Such substrates have been used to detect caspase activity and cytochrome P450 activity, among others.

Supplier: Tonbo Biosciences

The 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).

Supplier: Rockland Immunochemical

Anti-Orf2 Antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). The multi-functional nuclear protein ORF2p is involved in reverse transcriptase and endonuclease processes. ORF2 elements are epigenetically silenced throughout embyronic development and it is suggested that mutations of L1 would result in detrimental de novo insertions into the genome, negatively affecting gene expression.  L1 elements are critical components in the mammalian genome, and much is still not known regarding these proteins. Studies implicate that line-1 is activated in fetal oocytes and  L1ORF2p may contribute to the eradication or selection of the oocytes.

Supplier: Tonbo Biosciences

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.

Supplier: Rockland Immunochemical

Anti-p38 MAP kinase Antibody is recommended for use in WB, IP, and ELISA. Expect a band approximately ~38kDa Protein corresponding to the molecular mass of p38a MAPK on SDS PAGE immunoblots.

Supplier: Rockland Immunochemical

Anti-IgG Goat Polyclonal Antibody (AP (Alkaline Phosphatase))

Supplier: Tonbo Biosciences

Goat anti-Chicken IgY (H&L) - Affinity Pure, FITC Conjugate

Supplier: Rockland Immunochemical

Anti-Sheep IgG (H&L) peroxidase conjugated antibody is suitable for immunoblotting (western or dot blot), ELISA, immunoperoxidase electron microscopy and immunochemistry as well as other peroxidase-antibody based enzymatic assays requiring lot-to-lot consistency.

Supplier: Rockland Immunochemical

This monoclonal antibody is suitable for immunofluorescence microscopy, FLISA and western blotting. Expect a band approximately 56 kDa in size corresponding to phosphorylated AKT Protein by western blotting in the appropriate cell lysate or extract.

Supplier: Rockland Immunochemical

This purified antibody has been tested for use in ELISA and western blotting. Reactivity is also expected in neutralizations, radioimmunoassay and immunochemistry. The endotoxin content is estimated to be <10 pg/µl by the LAL method.

Supplier: Tonbo Biosciences

Goat anti-Mouse IgG Fc - Affinity Pure, HRP Conjugate

Supplier: Rockland Immunochemical

100ug. Clone: 33D10.D2. Immunogen: This antibody was prepared by repeated immunizations of mice with a synthetic peptide corresponding to the 6X HIS epitope tag (H-H-H-H-H-H) conjugated to KLH using maleimide.

Supplier: Rockland Immunochemical

ERK2 antibodies detect the ERK2 isoform. Mitogen activiated protein kinase 1, also known as MAPK1, ERK, or ERK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

Supplier: Rockland Immunochemical

ERK1 antibodies detect the ERK1 isoform. Mitogen activiated protein kinase 3, also known as MAPK3, ERK, or ERK1, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK1 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

Supplier: Rockland Immunochemical

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms.  Apoptosis is induced by certain cytokines in the TNF family, including TNF and Fas ligand, through their death domain containing receptors, TNFR1 and Fas.  A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4).  The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells. Anti-DR4 antibody is ideal for investigators involved in Apoptosis and Cytokines and Growth Factors.

Supplier: Tonbo Biosciences

The HI100 antibody reacts with the human CD45 isoform known as CD45RA, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RB, CD45RO and others.