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Specifications
- Antibody type:Primary
- Antigen name:Ribosomal Protein S6
- Clonality:Polyclonal
- Gene ID:6194
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:RPS6
- Conjugation:Unconjugated
- Western blot:Yes
- Antigen synonyms:Phosphoprotein NP33,RPS6,40S ribosomal protein S6,S6,OK/SW-cl.2
- Modification:phospho-Ser235/Ser236
- Storage buffer:Preservative: 0.05% Sodium Azide; Constituents: Dulbecco's PBS without magnesium and calcium, 50% Glycerol, PBS, 1mg/ml BSA, pH 7.3
- Storage temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Immunogen:Synthetic peptide derived from the region of human RPS6 that contains serines 235 and 236 (unfortunately, the amino acid sequence is considered to be commercially sensitive)
- Tested applications:WB
- Purification:Immunogen affinity purified
- Cat. no.:89359-522
Specifications
About this item
40S ribosomal protein S6 (also known as RPS6) is a ~31 kDa substrate of p70 S6 kinase (p70S6K) and a major component of translational machinery involved in protein synthesis, cell growth, proliferation, and metabolism. RPS6 undergoes phosphorylation on multiple serines in the carboxyl terminal region in the order 236-->235-->240-->244-->247, due to the positions of these amino acid residues on the alpha-helix. Hyperphosphorylation of RPS6 stimulates protein synthesis that mediates progression through the cell cycle.
WB: Use at a dilution of 1/1000. Predicted molecular weight: approx. 31 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: RPS6
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human