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Specifications
- Antibody type:Primary
- Antigen name:Regulator of G-protein Signaling 4
- Clonality:Polyclonal
- Gene ID:5999
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:RGS4
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:100 μl
- Western blot:Yes
- Antigen synonyms:RP11-430G6.1,MGC60244,MGC2124,SCZD9,RGP4,DKFZp761F1924
- Storage buffer:0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Molecular weight:23 kDa
- Storage temperature:Keep as concentrated solution. Aliquot and store at –20 °C or below. Avoid multiple freeze-thaw cycles.
- Concentration:0.43 mg/ml
- Immunogen:Recombinant protein encompassing a sequence within the center region of human RGS4. The exact sequence is proprietary.
- Tested applications:IHC-P
- Purification:Purified by antigen-affinity chromatography.
- Cat. no.:89357-930
Specifications
About this item
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Type: Primary
Antigen: RGS4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human