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Anti-IL12 Rat Monoclonal Antibody
Anti-IL12 Rat Monoclonal Antibody
Catalog # 89363-466
Supplier:  Genetex
Anti-IL12 Rat Monoclonal Antibody
Catalog # 89363-466
Supplier:  Genetex
Supplier Number:  GTX41390

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Interleukin 12
  • Antigen symbol:
    IL12
  • Clonality:
    Monoclonal
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • Flow cytometry:
    Yes
  • Host:
    Rat
  • Isotype:
    IgG2a
  • Reactivity:
    Mouse
  • Antigen synonyms:
    IL-12|cytotoxic lymphocyte maturation factor 35 kDa subunit|NK cell stimulatory factor chain 1|interleukin-12 subunit alpha|p35|natural killer cell stimulatory factor 1|interleukin-12 alpha chain|interleukin 12|IL-12 subunit p35|CLMF p35|cytotoxic lymphocyte maturation factor 1|subunit p35|35 kD subunit|NF cell stimulatory factor chain 1
  • Storage buffer:
    Preservative: 0.9% Sodium Azide. Constituents: PBS. pH 7.2
  • Storage temperature:
    Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
  • Immunogen:
    CHO expressed, recombinant mouse IL12 p70
  • Tested applications:
    Enzyme-linked ImmunoSpot, Fluorescence-Activated Cell Sorting
  • Purification:
    Protein A purified
  • Cat. no.:
    89363-466
  • Supplier No.:
    GTX41390

Specifications

About this item

Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells; costimulation of PBL proliferation; proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10; homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.

Type: Primary
Antigen: IL12
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG2a
Reactivity: Mouse