Anti-IL12 Rat Monoclonal Antibody
Catalog # 89363-466
Supplier: Genetex
Specifications
- Antibody type:Primary
- Antigen name:Interleukin 12
- Antigen symbol:IL12
- Clonality:Monoclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Flow cytometry:Yes
- Host:Rat
- Isotype:IgG2a
- Reactivity:Mouse
- Antigen synonyms:IL-12|cytotoxic lymphocyte maturation factor 35 kDa subunit|NK cell stimulatory factor chain 1|interleukin-12 subunit alpha|p35|natural killer cell stimulatory factor 1|interleukin-12 alpha chain|interleukin 12|IL-12 subunit p35|CLMF p35|cytotoxic lymphocyte maturation factor 1|subunit p35|35 kD subunit|NF cell stimulatory factor chain 1
- Storage buffer:Preservative: 0.9% Sodium Azide. Constituents: PBS. pH 7.2
- Storage temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Immunogen:CHO expressed, recombinant mouse IL12 p70
- Tested applications:Enzyme-linked ImmunoSpot, Fluorescence-Activated Cell Sorting
- Purification:Protein A purified
- Cat. no.:89363-466
- Supplier No.:GTX41390
Specifications
About this item
Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells; costimulation of PBL proliferation; proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10; homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.
Type: Primary
Antigen: IL12
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG2a
Reactivity: Mouse