Specifications
- Antibody type:Primary
- Antigen name:Cytochrome C
- Antigen symbol:CYCS
- Clonality:Monoclonal
- Clone:SJL2-4(apo)
- Conjugation:Unconjugated
- Host:Mouse
- Isotype:IgG2b
- Reactivity:Goat
- Western blot:Yes
- Size:50 μg
- Gene ID:54205
- Antigen synonyms:cyt c|HCS|THC4|CYC
- Storage buffer:Preservative: 0.02% Sodium Azide; Constituents: PBS
- Storage temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Concentration:1 mg/ml
- Immunogen:Recombinant full length protein (Horse).
- Tested applications:WB
- Purification:>95% by SDS-PAGE
- Cat. no.:89360-140
- Supplier No.:GTX16076
Specifications
About this item
Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production of cellular ATP. An increasing amount of interest has been directed toward the role which cytocrome C has been demonstrated to play in apoptotic processes. Following exposure to apoptotic stimuli, cytochrome C is rapidly released from the mitochondria into the cytosol, an event which may be required for the completion of apoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
WB: Use at a concentration of 1 ?g/ml. Detects a band of approximately 12 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: CYCS
Clonality: Monoclonal
Clone: SJL2-4(apo)
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: