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Specifications
- Antibody type:Primary
- Antigen name:Ataxia Telangiectasia mutated
- Antigen symbol:ATM
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Goat
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Size:50 μl
- Antigen synonyms:ATM Protein Kinase pS1981
- Gene ID:472
- Concentration:1.0 mg/ml
- Immunogen:Synthetic peptide (Human) - which represents a portion of human Ataxia Telangiectasia Mutated (ATM) proteinencoded within exon 53.
- Purification:Affinity purified with antigen
- Storage buffer:0.1ml Tris-citrate/phosphate, pH 7-8, with 0.1% sodium azide
- Storage temperature:Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
- Tested applications:IP, WB
- Cat. no.:89351-816
- Supplier No.:GTX22631
Specifications
About this item
ATM is a 370 kDa nuclear phosphoprotein, involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation and response to DNA repair. The C-terminal region has extensive homology to the catalytic domains of phosphatidyl inositol 3-kinases (PI3 kinases). Its usefulness to monitor altered ATM expression in cancer is under active investigation.
For IP: Use at a concentration of 10 - 20 ?g/mg cell lysate. For WB: Use at a dilution of 0.1 - 0.4 ?g/mg. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: ATM
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Goat
Isotype: IgG
Reactivity: Human