Caffeic acid
Caffeic acid, Sigma-Aldrich®
Supplier: MilliporeSigma
3,4-Dihydroxycinnamic acid for synthesis
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Caffeic acid
Supplier: Abcam
(IC₅₀ = 0.85 mM). Blood-brain barrier permeable.
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Caffeic acid predominantly trans 98+%
Supplier: Thermo Scientific Chemicals
Inhibitor of ornithine decarboxylase and protein tyrosine kinase
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Caffeic acid, Calbiochem®
Supplier: MilliporeSigma
A natural dietary compound reported to have anticarcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50=3.7µM). Inhibits Ca2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
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