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1506 Resultaten voor: "single-use assemblies"

System waste caps LC, b.safe

System waste caps LC, b.safe

Supplier: Bohlender

b.safe waste tubes can be connected to the canister by means of these b.safe system waste caps and solvents can be collected safely. To avoid spill over of canisters through the connection of a Waste Cap to a b.safe Display for electronic level control. The filling levels of waste containers in laboratory cupboards and workbenches can be reliably monitored. With the use of b.safe Waste Tubes, solvent waste is led directly into the canister, solvent vapours are held back by the exhaust filter with activated carbon or can be led to the hood by means of a venting hose.

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ESD safety shoes, sandals, Velcro® fastening, Scott

ESD safety shoes, sandals, Velcro® fastening, Scott

Supplier: ELTEN

100% metal- and leather-free, lightweight ESD safety sandal made from microfibre and textile upper, reflective materials, a padded tongue plus a slip resistant, dual-density TPU/PU sole (Sportics).

    
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Human recombinant beta-2-Microglobulin (from E. coli)

Supplier: ProSci Inc.

beta -2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecules, involved in the presentation of peptide antigens to the immune system. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. B2M has been shown as a marker for monitoring inflammatory disease activity and it appears likely to have a destructive role in amyloidosis-related arthritis. B2M might be involved in the OA (osteoarthritis) pathogenesis. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation. B2M could be a potential therapeutic target in ovarian cancer.

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Corning Life Sciences

Why Choose Corning Fetal Bovine Serum?

Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.

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VWR®, Crimp Neck Vials ND11

VWR®, Crimp Neck Vials ND11

Supplier: VWR Collection

ND11 crimp neck vials are manufactured from 1st hydrolytic class borosilicate glass with flat bottom. They can be purchased with a variety of aluminium seal styles and septa materials.

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Anti-CD3 Rat Monoclonal Antibody [clone: 17A2] (APC)

Anti-CD3 Rat Monoclonal Antibody [clone: 17A2] (APC)

Supplier: STEMCELL Technologies

Rat monoclonal antibody against mouse CD3, APC-conjugated.

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Anti-CD3 Rat Monoclonal Antibody [clone: 17A2] (FITC)

Anti-CD3 Rat Monoclonal Antibody [clone: 17A2] (FITC)

Supplier: STEMCELL Technologies

Rat monoclonal antibody against mouse CD3, FITC-conjugated.

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Human recombinant IFN alpha (from cells)

Supplier: ProSci Inc.

The Interferon- alpha/ beta Receptor 1 (IFN- alpha/ beta R1) is a receptor which binds Type I Interferons including Interferon- alpha and - beta . It is a cell surface receptor and heteromeric receptor composed of one chain with two subunits referred to as IFNAR1 and IFNAR2. IFN- alpha/ beta R1, in association with IFN- alpha/ beta R2, is required for propagating antiviral signal transduction triggered by IFN- alpha and IFN- beta . IFN- alpha/ beta R1 interacts very weakly or not at all with type 1 interferons and does not stably interact with IFN- alpha/ beta R2. Ligands associate with IFN- alpha/ beta R2, and this complex subsequently forms a stable ternary assembly with IFN- alpha/ beta R1. IFN- alpha/ beta R1 also associates with IFN- gamma R2 even in the absence of IFN- gamma stimulation. Human IFN- alpha/ beta R1 contains a nuclear localization signal in its extracellular domain that is required for receptor translocation to the nucleus following interaction with ligand. Interferon stimulation results in an immunologic response that is especially associated with viruses.

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One step RT-PCR master mix kit

Supplier: Merck Millipore (Novagen)

The One Step RT-PCR Master Mix Kit allows rapid, sensitive analysis of gene expression from tissues and cells. It can replace methods for detecting and quantifying gene expression such as Northern blots, in situ hybridisation, dot blots, S nuclease assays and conventional two step RT-PCR. The kit utilises recombinant Thermus thermophilus (rTth) DNA Polymerase, which acts as both a thermostable RNA dependent DNA polymerase and a DNA dependent DNA polymerase. The rTth DNA Polymerase is provided in a 2X master mix with an antibody for antibody-mediated hot start, optimised buffer, and ultrapure deoxynucleotides. Antibody-mediated Hot Start enhances specificity of both reverse transcription and PCR. The kit enables cDNA synthesis from input RNA followed by PCR amplification of the cDNA in a single reaction, with no additional hands-on requirement for buffer changes or adding reagents. Typically, detection of a specific transcript requires only 2 hours.

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Flat Flange Lids for Glass Reactors

Flat Flange Lids for Glass Reactors

Supplier: S.C.A.T.

The flat flange lid is usually placed between two flanges to be joined and then tightened with bolts to create a secure connection. Suitable for glass reactors with a SCHOTT flat flange.

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MELLI S1P ESD Safety Sandals for Ladies, Grey

MELLI S1P ESD Safety Sandals for Ladies, Grey

Supplier: ELTEN

Ladies' safety sandal, MELLI, Velcro® closure in grey finish.

    
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Slim Jim® Confidential Document Containers

Slim Jim® Confidential Document Containers

Supplier: Rubbermaid Commercial Products

Slim Jim® confidential document containers are ideal for placement under desks, nursing stations, and counters for secure and convenient access.

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Table/workbench, with optional add-on storage units or rear rail only

Table/workbench, with optional add-on storage units or rear rail only

Supplier: TEKNOMEK

High quality, fully welded 304 grade stainless steel workbench with rear rail, sturdy, hygienic and built to last. Choice of mobile or static, with option to add-on storage units too.

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BRICE Air XXTM S1P ESD Safety Shoes, Black, Low

BRICE Air XXTM S1P ESD Safety Shoes, Black, Low

Supplier: ELTEN

Safety slip-on shoes, BRICE Air XXTM black Low ESD S1P.

    
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MELLI S1P ESD Safety Shoes for Ladies, Grey, Low

MELLI S1P ESD Safety Shoes for Ladies, Grey, Low

Supplier: ELTEN

Ladies' safety shoe, MELLI, lace-up in grey finish.

    
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Anti-CD3 Rat Monoclonal Antibody [clone: 17A2]

Anti-CD3 Rat Monoclonal Antibody [clone: 17A2]

Supplier: STEMCELL Technologies

Rat monoclonal antibody against mouse CD3, unconjugated.

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Screw neck vials, N 10

Screw neck vials, N 10

Supplier: MACHEREY-NAGEL

These screw neck vials have a wide opening for easy filling.

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Human recombinant beta-2-Microglobulin (from Cells)

Supplier: ProSci Inc.

beta -2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecules, involved in the presentation of peptide antigens to the immune system. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. B2M has been shown as a marker for monitoring inflammatory disease activity and it appears likely to have a destructive role in amyloidosis-related arthritis. B2M might be involved in the OA (osteoarthritis) pathogenesis. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation. B2M could be a potential therapeutic target in ovarian cancer.

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Human Recombinant PDGF-AB

Human Recombinant PDGF-AB

Supplier: STEMCELL Technologies

Platelet-derived growth factor (PDGF) is a dimeric glycoprotein consisting of two disulfide bridge-stabilized polypeptide chains, A and B, which are assembled as heterodimers (PDGF-AB) or homodimers (PDGF-AA and PDGF-BB) (Fretto et al.; Westermark and Heldin). PDGF signals through the receptor tyrosine kinases PDGFRalpha and PDGFRbeta. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al.). PDGF is a potent mitogen for cells of mesenchymal origin- like fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto et al.; Sachinidis et al.). It has been shown that PDGF-AB together with 5-Azacytidine (Catalog #72012), induces the conversion of mature bone and fat cells into tissue-regenerative multipotent stem cells (Chandrakanthan et al.).

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C columns

C columns

Supplier: Cytiva

C columns are economical empty columns suitable for low pressure liquid chromatography and gravity feed at the lower volumes used at research scale.

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Fraction collector, refrigerated, CMA 470

Supplier: HARVARD APPARATUS

The CMA 470 refrigerated fraction collector is specifically designed to collect microliter volume fractions typical of microdialysates. It is a stand alone instrument, but it is equipped with a digital input/output port and an RS232 interface for connection to the software.

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Sleeve protector, cut resistant, Helix C500

Sleeve protector, cut resistant, Helix C500

Supplier: UVEX

These sleeve protectors are manufactured using the Bamboo TwinFlex® technology, a material composition made of a cut protection fibre on the outside and a bamboo comfort fibre on the inside.

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Matrix Plus, CELLvo™

Matrix Plus, CELLvo™

Supplier: STEMBIOSYS

CELLvo™ Matrix Plus is a substrate that aims to recapitulate the biochemical, structural and mechanical cues of the native niche by leaving the extracellular matrix intact. Cell-derived matrices create a biologically relevant culture environment for a variety of cell types including pluripotent cells by providing all the cues cells expect to receive in vivo in culture dishes.

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Chemical resistant overalls, MICROCHEM® 4000 AVANT AIRline, Model 755

Supplier: Ansell

Encapsulated chemical protective suits for use with air-fed/supplied systems.

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ESD safety shoes, lace-up, Fun, Maverick Blue Low

ESD safety shoes, lace-up, Fun, Maverick Blue Low

Supplier: ELTEN

Sporty, lightweight, leather-free ESD safety shoe made from microfibre and mesh inserts, a padded tongue plus a slip resistant, dual-density PU/PU sole (Fun).

    
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Cleanroom vacuum cleaner, CR-1200D

Cleanroom vacuum cleaner, CR-1200D

Supplier: TIGER-VAC

New generation cleanroom vacuum cleaners available in dry recovery. Designed specifically for the pharmaceutical, semiconductor and microelectronics industry.

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Nitril handschoenen, Microflex® 93-856

Nitril handschoenen, Microflex® 93-856

Supplier: Ansell

These disposable gloves resist a variety of industrial chemicals for longer periods than other disposable nitrile gloves.

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Almatec Air-driven Postive Displacement Pumps

Almatec Air-driven Postive Displacement Pumps

Supplier: Avantor Fluid Handling

German precision engineered AODD pumps to get your application up and flowing.

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Rotary evaporator, large scale, Rotavapor® R-250 EX

Rotary evaporator, large scale, Rotavapor® R-250 EX

Supplier: BUCHI

The Rotavapor R-250 EX is the EX rated version of the Rotavapor R-250. It fulfills the high requirements of the ATEX regulations and fits perfect to your Ex-proof production laboratory. It is designed for easy and safe operation combined with high performance.

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Mouse Recombinant PDGF-BB

Mouse Recombinant PDGF-BB

Supplier: STEMCELL Technologies

The platelet-derived growth factor (PDGF) family has five heparin-binding members that assemble into four homodimers (PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD) and one heterodimer (PDGF-AB; Fretto et al.; Li and Eriksson). PDGF signals through the receptor tyrosine kinases PDGFRα and PDGFRβ. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al.). PDGF is a potent mitogen for cells of mesenchymal origin, such as fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto et al.; Sachinidis et al.). PDGF-BB is secreted by osteoblasts to induce mesenchymal stem cell migration and angiogenesis. It has also been shown that PDGF-BB is secreted by preosteoclasts during bone modeling and remodeling to induce angiogenesis and thus proper osteogenesis (Xie et al.).

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General purpose gloves, Showa 370

Supplier: Showa

These lightweight palm-coated nylon gloves are ideal for protecting hands against fluids such as oils. They allow finger dexterity to be maintained whilst being robust and hard-wearing.

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