"drives"

Supplier: Bioss

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).

Supplier: THERMO H + P LABORTECHNIK

Disc motor drive stirrers and accessory Telemodul controller, which can stir very large liquid volumes and mix highly viscous media. Stirrers have ultra-flat, space-saving design with housing that is easy-to-clean under running water.

Supplier: Avantor Fluid Handling

Optimize performance of your Flux® centrifugal pump.

Supplier: IKA

Stainless steel platform extension for I-MAG, for barrels up to 150 litres (I-MAG SP 150). Maximum load of 200 kg, for vessels with Ø 300 - 500 mm. Barrels or vessels used only stand on the set-up frame and not directly on the I-MAG drive unit. This allows the drive unit to be simply pulled out from under the barrel, without having to move the vessel standing on it which facilitates flexible use of the unit

Supplier: BELLCO GLASS

5-position base

Supplier: Bioss

Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Supplier: Bioss

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).

Supplier: Bioss

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).

Supplier: THERMO H + P LABORTECHNIK

Perform powerful resonance shaking up to 8500 min⁻¹ with Thermo Scientific™ Teleshake 1536-8 Magnetic Microtiter Plate Shakers, which feature a wear-free magnetic drive. They are remote controlled for integrated shaking applications, and are suited for 1536- and 384-well microtiter plates.

Supplier: VWR Collection

De UH5200 heeft een 10,4" gekleurde achtergrondverlichte LCD-display met 800×600 pixelresolutie voor gedetailleerde weergave van kalibratiecurven en gemeten spectra. UH5200 is een stand-alone instrument dat ook vanaf een pc bediend kan worden met de optionele UV Solutions Plus-software. Geregistreerde meetgegevens kunnen in het instrumentgeheugen of op USB-drives worden opgeslagen.

Supplier: Bioss

Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

Supplier: Bioss

Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

Supplier: Avantor Fluid Handling

Optimize performance of your Levitronix Centrifugal Pump.

Supplier: Avantor Fluid Handling

Compacte, kosteneffectieve pompsystemen voor algemene toepassingen voor vloeistofoverdracht.

Supplier: Bioss

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).

Supplier: SP Industries

These dewar Flasks provide a convenient alternative to VT systems for studies at 77 K, and are silvered around the reservoir. 150 ml flask lasts 30 minutes after a filling. The offset versions (WG-853) are designed for cavities that have limited space between the reservoir and the drive shaft for iris.