"Staining Solutions"
Anti-KRT17 Mouse Monoclonal Antibody [clone: SPM560]
Supplier: ProSci Inc.
Cytokeratin 17 (CK17) is a member of the Cytokeratin subfamily of intermediate filament proteins (IF's). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. CK17 is expressed in the nail bed, hair follicle, sebaceous glands and other epidermal appendages. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered an epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 can be useful when included in a panel of antibodies against TTF-1, napsin A, CK5&6, p63, and SOX-2 for diagnostic differentiation between lung adenocarcinoma (LADC) and lung squamous cell carcinoma (SCLC), especially for poorly-differentiated lung carcinoma. CK17 is expressed in SCLC much higher than in LADC. In breast carcinomas, approximately 20% of patients show no expression of ER, PR and Her2, which are defined as triple negative tumor. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
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COMMASSIE BLUE STAINING DESTAING SOLUTIO 1 * 1 Kit
Supplier: Boster Bio
COMMASSIE BLUE STAINING DESTAING SOLUTIO 1 * 1 Kit
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SCHIFF REAGENT SOLUTION 500 1 * 500 mL
Supplier: G-Biosciences
SCHIFF REAGENT SOLUTION 500 1 * 500 mL
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SCHIFF REAGENT SOLUTION 125 1 * 125 mL
Supplier: G-Biosciences
SCHIFF REAGENT SOLUTION 125 1 * 125 mL
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GELITE SAFE DNA GEL STAIN 1 * 10 µl
Supplier: AAT Bioquest
GELITE SAFE DNA GEL STAIN 1 * 10 µl
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[EN]GREENGEL DNA STAIN 10000X STOCK SOLU 1 * 500 µl
Supplier: EMBITEC
[EN]GREENGEL DNA STAIN 10000X STOCK SOLU 1 * 500 µl
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[EN]GREENGEL DNA STAIN 10000X STOCK SOLU 1 * 50 µl
Supplier: EMBITEC
[EN]GREENGEL DNA STAIN 10000X STOCK SOLU 1 * 50 µl
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ETHIDIUM HOMODIMER I SOLUTION IN DMSO 1 * 1 mL
Supplier: ION BIOSCIENCES
ETHIDIUM HOMODIMER I SOLUTION IN DMSO 1 * 1 mL
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GRAM-HÜCKER L SLOW ACTION 4X240ML 1 * 1 Kit
Supplier: RAL
GRAM-HÜCKER L SLOW ACTION 4X240ML 1 * 1 Kit
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