12531 Resultaten voor: "ENZO LIFE SCIENCES"
Anti-CYP2B6 Sheep Polyclonal Antibody
Supplier: Enzo Life Sciences
Phenobarbital is well established as a potent inducer of cytochrome P-450 2B (CYP2B) expression, and work by different groups has shown that AP-1 might play a role in the induction process, and that insulin is able to supress the effect of phenobarbital. Human CYP2B6 appears to be the primary enzyme involved in the N-demethylation of S-mephenytoin and may contribute to the hepatic metabolism of toluene to benzyl alcohol.
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Anti-LAMP3 Mouse Monoclonal Antibody (Alexa Fluor® 546) [clone: 104G4]
Supplier: Enzo Life Sciences
Recommended Applications: IF, IHC (FS)
Species reactivity: Human, Sheep
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Anti-APP Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Recommended Applications: IHC
Species reactivity: Rodent
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
Anti-CYP2D6 Sheep Polyclonal Antibody
Supplier: Enzo Life Sciences
Human cytochrome P-450 2D6 (CYP2D6) is responsible for the metabolism of many psychotherapeutic drugs, and has been shown to act on MPTP a thermal product of synthetic heroin, which causes Parkinson's Disease (PD)-like symptoms in man. Mutation in the cyp2D6 gene has been reported to be associtated with PD. The association between Parkinson's Disease and genetic polymorphism in the human CYP2D6 gene has been reported. CYP2D6 has been found in first trimester human fetal liver, and in the placenta. Rat CYP2D1, the homolgue of human CYP2D6, has been shown to catalyse the conversion of hydrocodone to hydromorphone, and in rat liver microsomes it participates in the conversion of ethylmorphine to codeine and morphine.
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Monastrol ≥98% (by TLC)
Supplier: Enzo Life Sciences
Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.
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Anti-VTN Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Vitronectin is a plasma glycoprotein that circulates in the blood as a mixture of both 75kDa and 65kDa forms. Vitronectin is a major cell adhesive glycoprotein, and a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins, and often participates in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin, which is recognized by its integrin receptor.
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Anti-Complement C9 Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Complement factor C9 is a 71kDa single-chain ellipsoid a-globular molecule of 558 amino acids including a leader sequence of 20 amino acids. C9 binds the C5b8 complex on membranes and has the unique function of forming tubular structures containing between 12 and 18 monomers, closely resembling the membrane attack complex (MAC). The primary site of synthesis is hepatocytes; secondary sites are monocytes, fibroblasts and glial cells. The normal level of C9 in plasma is 60 µg/ml, and the level is upregulated from hepatocytes by IFN-γ.
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Anti-L-Ficolin Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups, thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP (MBL-associated serine protease).
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Anandamide ≥98% (by TLC)
Supplier: Enzo Life Sciences
Endogenous [1] ligand for the CB1 receptor (CB1: Ki=52nm; CB2: Ki=1930nm [2]) and TRPV1 (Ki=5.78µM [3,4]). Inhibits NF-κB activation through direct binding to IKKβ [5] and induces apoptosis independently of cannabinoid or vanilloid receptors [6]. Activates the MAP kinase (MAPK/ERK) signalling pathway [7].
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N-Arachidonyl-2-chloroethylamide ≥98% (by TLC)
Supplier: Enzo Life Sciences
Cannabinoid receptor ligand.
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Linoleamide ≥98% (by TLC), white solid
Supplier: Enzo Life Sciences
Unsaturated analog of endogenous sleep inducing lipid.
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Noladin ether ≥98% (by TLC)
Supplier: Enzo Life Sciences
Cannabinoid receptor ligand.
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Aristoforin ≥95%
Supplier: Enzo Life Sciences
Stable and water-soluble derivative of hyperforin inducing apoptosis. Antitumor agent. Inhibits sirtuins.
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Human recombinant NF-kappaB (p50) (from insect cells (Sf9)), HIS tag
Supplier: Enzo Life Sciences
Produced in SF21 cells. Fused to a His-tag.
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Human recombinant Minor vault p193 protein (from E. coli), HIS Tag
Supplier: Enzo Life Sciences
Produced in E. coli. Catalytic domain of human minor vault p193 protein (aa 220-574) is fused at the C-terminus to a His-tag.
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Matrix metalloproteinase
Supplier: Enzo Life Sciences
Enzyme regulation and kinetics, comparative studies of substrate or inhibitor specificities, cleavage of target proteins. Assay or digest conditions can vary widely, but concentrations for the MMP enzymes can range between 10 and 300nM, or higher. Reaction temperatures can be between 25 and 37 °C, and reaction times can range from 10 min to overnight, again depending on application and substrate. A typical assay buffer is 50 mM HEPES, pH 7,0, 10 mM CaCl₂, 0,05% Brij-35. For more information, contact Enzo Life Sciences Technical Support.
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CV-Cathepsin B detection kit
Supplier: Enzo Life Sciences
Based on the dye cresyl violet and the cathepsin B ArgArg peptide recognition sequence, this kit allows the detection of cathepsin B activity in living cells by fluorescence microscopy.
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Quantipak™ Caspase fluorescent (AMC) kit
Supplier: Enzo Life Sciences
Fluorescent substrates plus inhibitors to greatly increase sensitivity. Mainly used for Fluorescent detection and HTS activity assay.
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Human thrombin (from plasma)
Supplier: Enzo Life Sciences
Isolated from human plasma as prothrombin, and activated with Factor Xa, Factor Va, phospholipids, and calcium to yield a-thrombin.
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Matrix Metalloproteinase-1 (MMP-1) colorimetric drug discovery kit
Supplier: Enzo Life Sciences
A QuantiZyme™ Assay System. The MMP-1 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-1 (MMP-1, interstitial collagenase, fibroblast collagenase) using a thiopeptide as a chromogenic substrate.
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Anti-PARP1 Mouse Monoclonal Antibody [clone: C-2-10]
Supplier: Enzo Life Sciences
Anti-PARP1 Mouse Monoclonal Antibody [clone: C-2-10]
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Anti-CDK1 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Host: Rabbit
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Anti-COX-2 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Host: Rabbit
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Anti-CALPAIN II Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG1
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Anti-Y Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG2b
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Anti-Y Mouse Monoclonal Antibody (Biotin) [clone: ]
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG2b