12530 Resultaten voor: "ENZO LIFE SCIENCES"

Supplier: ENZO LIFE SCIENCES

Blocks slow voltage-sensitive L-type Ca²⁺ channels. Adrenergic antagonist. Inhibits platelet-activating factor and PMA-stimulated prostaglandin production in Kupffer cells. Induces apoptosis. In vitro resistance modifier in drug resistant human tumor cell lines.

Supplier: ENZO LIFE SCIENCES

Protein kinase inhibitor

Supplier: ENZO LIFE SCIENCES

Host: Rabbit

Supplier: ENZO LIFE SCIENCES

TNF-alpha converting enzyme (TACE) is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), and is responsible for the cleavage of membrane-bound precursor TNF-alpha to its mature, secreted form. TACE also processes other cell surface proteins, including TNF receptor, TGFalpha, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP).

Supplier: ENZO LIFE SCIENCES

Potent and selective inhibitor of VEGFR-2 (Flk-1, KDR). It displays a 100-fold greater potency for the unactivated form of the kinase (Ki=0.04µM) compared to the activated form (Ki=4µM).

Supplier: ENZO LIFE SCIENCES

Xestonspongin C is a structurally novel marine alkaloid isolated from the Okinawan sponge Xestospongia sp. It is a potent, cell-permeable inhibitor of IP3 receptor-mediated Ca²⁺ release (IC50 = 358 nM). However, since xestospongin C also inhibits voltage-dependent Ca²⁺ and K⁺ currents at concentrations similar to those which inhibit the IP3 receptor, it can only be regarded as a selective blocker of the IP3 receptor in permeabilized cells and not in cells with intact plasma membranes. Has vasodilatory properties.

Supplier: ENZO LIFE SCIENCES

Produced in CHO cells. The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).

Supplier: ENZO LIFE SCIENCES

Produced in E. coli. E. coli DnaJ is fused at the N-terminus to a His-tag.

Supplier: ENZO LIFE SCIENCES

Fluorogenic substrate for several matrix metalloproteinases (MMPs).

Supplier: ENZO LIFE SCIENCES

Screen-Well™ REDOX library contains 84 compounds with defined prooxidant or antioxidant activity.

Supplier: ENZO LIFE SCIENCES

The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members.

Supplier: ENZO LIFE SCIENCES

TMP-153 is a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), IC50=5-10 nM. It inhibits cholesterol absorption and lowers plasma cholesterol in rats and hamsters. ACAT inhibitors improve plasma lipid profile and ameliorate proteinuria in nephrotic animals.

Supplier: ENZO LIFE SCIENCES

Most comprehensive portfolio of heat shock protein (chaperone) products commercially available.

Supplier: Enzo Life Sciences

Anti-COP9 Antibody

Supplier: ENZO LIFE SCIENCES

PKC inhibitor

Supplier: ENZO LIFE SCIENCES

Produced in E. coli.

Supplier: ENZO LIFE SCIENCES

CEACAM1 (CD66a, BGP) belongs to the carcinoembryonic antigen (CEA) gene family. It is expressed on cells of epithelial and myeloid origin. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A (A1, A2) and one B domain. While N, A1 and B domains can also be found in other CEA-family members, the A2 domain of CEACAM1 differs from those found in other CEACAMs.

Supplier: ENZO LIFE SCIENCES

Recommended Applications: Flow Cytometry, IF, IHC (FS)

Species reactivity: Human, Dog

Supplier: ENZO LIFE SCIENCES

Na⁺/K⁺ ATPase inhibitor

Supplier: ENZO LIFE SCIENCES

Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterised by the presence of atleast one Bcl-2 homology (BH) domains.

Supplier: ENZO LIFE SCIENCES

Host: Mouse, Isotype: IgG1

Supplier: ENZO LIFE SCIENCES

Cell-permeable, potent and AMP-competitive inhibitor of glycogen phosphorylase.

Supplier: ENZO LIFE SCIENCES

Streptogramin antibiotic

Supplier: ENZO LIFE SCIENCES

Optimised standard PCR mix for enhanced speed, yield, and specificity. Used for standard PCR applications.

Supplier: ENZO LIFE SCIENCES

Recommended Applications: Flow Cytometry

Species reactivity: Human

Supplier: ENZO LIFE SCIENCES

Inhibitor of PLC activation

Supplier: ENZO LIFE SCIENCES

MAPKAPK substrate

Supplier: ENZO LIFE SCIENCES

For the quantitative determination of mouse TNF-α in culture supernatants and serum. Cited sample type includes tissue and plasma.

Supplier: ENZO LIFE SCIENCES

Endogenous signaling molecule.

Supplier: ENZO LIFE SCIENCES

mGluR5 antagonist.