Anti-DNA Ligase IV/LIG4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
BOSSBS-1677R-A680
: Bioss
- Type antilichaam:Primair
- Clonality:Polyklonaal
- Conjugatie:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemie:Yes
- ImmunoFluorescentie:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Epitoop:51-150/911
- Formulier:Liquid
- Gen-ID:3981
- Antigeen synoniemen:DNA ligase IV|Polydeoxyribonucleotide synthase [ATP] 4|LIG4S|DNA ligase 4|LIG4
- Modification:Unmodified
- Opslagbuffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Moleculair gewicht:104 kDa
- Opslagtemperatuur:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentratie:1 µg/µl
- Shipping temperature:4 °C
- Immunogeen:KLH conjugated synthetic peptide derived from human DNA Ligase IV
- Tested applications:ICC
- Purification:Purified by Protein A
- Verpakking:Vial
- VPE:100 µl
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Type: Primary
Antigen: DNA Ligase IV/LIG4
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 51-150/911
Host: Rabbit
Isotype: IgG
Reactivity: Human