Anti-DOK1 Tyr362 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
BOSSBS-5289R-A750
: Bioss
- Type antilichaam:Primair
- Clonality:Polyklonaal
- Conjugatie:Alexa Fluor® 750
- Flowcytometrie:Yes
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Formulier:Liquid
- Gen-ID:1796
- Antigeen synoniemen:DOK-1|p62dok|Docking protein 1 62kD|DOK1_HUMAN|Downstream of tyrosine kinase 1|DOK1 phospho Tyr362|P62DOK|DOK 1|docking protein 1 62kD downstream of tyrosine kinase 1|pp62|Docking protein 1|DOK1|DOK1 phospho Y362|p-DOK1 phospho Y362|docking protein 1 downstream of tyrosine kinase 1|Docking protein 1 p62dok Downstream of tyrosine kinase 1 pp62.
- Modification:Phosphorylation (Tyr362)
- Opslagbuffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Moleculair gewicht:62 kDa
- Opslagtemperatuur:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentratie:1 µg/µl
- Shipping temperature:4 °C
- Immunogeen:KLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr362
- Purification:Purified by Protein A
- Verpakking:Vial
- VPE:100 µl
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukaemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
Type: Primary
Antigen: DOK1 Tyr362
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human