Human recombinant FGF21 (from E. coli)

About this item

Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.

Animal-free
Produced from genetically modified E. coli
Monomeric protein containing 182 amino acids

Delivery: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Caution: This product is for research use only and is not for use in humans.

Specifications

Conjugatie:
Onconjugeerd
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Bron:
E. coli
Species:
Human
Storage conditions:
–20 °C
Endotoxinegehalte:
Endotoxin LAL (EU/µg) ≤0,1
Biologische activiteiten:
Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
Gen-ID:
Q9NSA1
Reconstitution instructions:
Sterile water at 0.1 mg/ml
Endotoxinevrij:
N
Dragervrij:
Y
Protease-free:
N
Diervrij:
Y
Protein synonyms:
Fibroblast Growth Factor-21|FGF-21|FGFL
Protein/peptide name:
FGF21
Zuiverheid:
≥95%
Moleculair gewicht:
19,5 kDa
Sequentie:
MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
Formulering:
10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
Vrij van nucleasen:
N
Nr:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay
Aminozuurgetal:
182