Dithiothreitol (DTT, Cleland's reagent) ≥99% for electrophoresis

Supplier: Thermo Fisher Scientific

Dithiothreitol (DTT, Cleland's reagent) ≥99% for electrophoresis

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Dithiothreitol (DTT, Cleland's reagent) ≥97%, Millipore®

Supplier: Merck Millipore (Calbiochem‎)

A protective agent for SH groups. Cyclizes as it reduces disulfides to thiols, so reaction is "driven" to completion. Does not contain waxy surfactant found in many other preparations.

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Dithiothreitol (DTT, Cleland's reagent) 1 M in water voor de biochemie

Supplier: Thermo Fisher Scientific

Dithiothreitol (DTT, Cleland's reagent) 1 M in water for biochemistry

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Dithiothreitol (DTT, Cleland's reagent) 99% voor de biochemie

Supplier: Thermo Fisher Scientific

Dithiothreitol (DTT, Cleland's reagent) 99% for biochemistry

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Dithiothreitol (DTT, Cleland's reagent) ≥99.5%, white powder for electrophoresis

Supplier: MP Biomedicals

DL-Dithiothreitol is also known as Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH). In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution. Disulfide reduction occurs quickly at pH 8.
Dithiothreitol is useful for stabilizing sulfhydryl containing enzymes. Effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N'-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol.
Useful for stabilizing sulfhydryl-containing enzymes.