1521 Résultats pour : "single-use assemblies"

Supplier: Rubbermaid Commercial Products

The HYGEN™ Quick-Connect handles and poles make cleaning more efficient in every area of the facility. The unique connection mechanism allows for easy, time-saving tool exchange.

Supplier: Corning

Polypropylene, translucent, graduated with red tamper evident HDPE screw caps.

Supplier: ProSci Inc.

beta -2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecules, involved in the presentation of peptide antigens to the immune system. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. B2M has been shown as a marker for monitoring inflammatory disease activity and it appears likely to have a destructive role in amyloidosis-related arthritis. B2M might be involved in the OA (osteoarthritis) pathogenesis. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation. B2M could be a potential therapeutic target in ovarian cancer.

Supplier: Spectrum Laboratories

The stainless steel Bessman tissue pulveriser consists of a two-component mortar with handles and a pestle, specifically designed for pulverising 10 - 1000 mg of tissue.

Supplier: Portwest

These gloves have a 13 g nylon and carbon fibre shell which diverts static electricity. They feature a durable PU coating on the palm.

Supplier: STEMCELL Technologies

Rat monoclonal antibody against mouse CD3, APC-conjugated.

Supplier: TEKNOMEK

High quality, fully welded 304 grade stainless steel workbench with rear rail, sturdy, hygienic and built to last. Choice of mobile or static, with option to add-on storage units too.

Supplier: Rubbermaid Commercial Products

Slim Jim® confidential document containers are ideal for placement under desks, nursing stations, and counters for secure and convenient access.

Supplier: MP Biomedicals

Vincristine Sulfate, a dimeric Vinca alkaloid. Experiments have reported Vincristine Sulfate to demonstrate a capacity to suppress growth of proliferating cells through marked apoptosis. The cell death caused by this agent seems to result in a sustained accumulation of endogenous ceramide levels. Ceramide, has been proposed as a lipid second messenger with specific antiproliferative mediating responses.

Supplier: STEMCELL Technologies

Rat monoclonal antibody against mouse CD3, FITC-conjugated.

Supplier: S.C.A.T.

The flat flange lid is usually placed between two flanges to be joined and then tightened with bolts to create a secure connection. Suitable for glass reactors with a SCHOTT flat flange.

Supplier: STEMCELL Technologies

Rat monoclonal antibody against mouse CD3, unconjugated.

Supplier: ELTEN

100% metal- and leather-free, lightweight ESD safety sandal made from microfibre and textile upper, reflective materials, a padded tongue plus a slip resistant, dual-density TPU/PU sole (Sportics).

Supplier: STEMBIOSYS

CELLvo™ Matrix Plus is a substrate that aims to recapitulate the biochemical, structural and mechanical cues of the native niche by leaving the extracellular matrix intact. Cell-derived matrices create a biologically relevant culture environment for a variety of cell types including pluripotent cells by providing all the cues cells expect to receive in vivo in culture dishes.

Supplier: UVEX

These sleeve protectors are manufactured using the Bamboo TwinFlex® technology, a material composition made of a cut protection fibre on the outside and a bamboo comfort fibre on the inside.

Supplier: MACHEREY-NAGEL

These screw neck vials have a wide opening for easy filling.

Supplier: Cytiva

C columns are economical empty columns suitable for low pressure liquid chromatography and gravity feed at the lower volumes used at research scale.

Supplier: ELTEN

Safety slip-on shoes, BRICE Air XXTM black Low ESD S1P.

Supplier: ProSci Inc.

beta -2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecules, involved in the presentation of peptide antigens to the immune system. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. B2M has been shown as a marker for monitoring inflammatory disease activity and it appears likely to have a destructive role in amyloidosis-related arthritis. B2M might be involved in the OA (osteoarthritis) pathogenesis. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation. B2M could be a potential therapeutic target in ovarian cancer.

Supplier: STEMCELL Technologies

Platelet-derived growth factor (PDGF) is a dimeric glycoprotein consisting of two disulfide bridge-stabilized polypeptide chains, A and B, which are assembled as heterodimers (PDGF-AB) or homodimers (PDGF-AA and PDGF-BB) (Fretto et al.; Westermark and Heldin). PDGF signals through the receptor tyrosine kinases PDGFRalpha and PDGFRbeta. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al.). PDGF is a potent mitogen for cells of mesenchymal origin- like fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto et al.; Sachinidis et al.). It has been shown that PDGF-AB together with 5-Azacytidine (Catalog #72012), induces the conversion of mature bone and fat cells into tissue-regenerative multipotent stem cells (Chandrakanthan et al.).

Supplier: Merck Millipore (Novagen)

The One Step RT-PCR Master Mix Kit allows rapid, sensitive analysis of gene expression from tissues and cells. It can replace methods for detecting and quantifying gene expression such as Northern blots, in situ hybridisation, dot blots, S nuclease assays and conventional two step RT-PCR. The kit utilises recombinant Thermus thermophilus (rTth) DNA Polymerase, which acts as both a thermostable RNA dependent DNA polymerase and a DNA dependent DNA polymerase. The rTth DNA Polymerase is provided in a 2X master mix with an antibody for antibody-mediated hot start, optimised buffer, and ultrapure deoxynucleotides. Antibody-mediated Hot Start enhances specificity of both reverse transcription and PCR. The kit enables cDNA synthesis from input RNA followed by PCR amplification of the cDNA in a single reaction, with no additional hands-on requirement for buffer changes or adding reagents. Typically, detection of a specific transcript requires only 2 hours.

Supplier: BUCHI

The Rotavapor R-250 EX is the EX rated version of the Rotavapor R-250. It fulfills the high requirements of the ATEX regulations and fits perfect to your Ex-proof production laboratory. It is designed for easy and safe operation combined with high performance.

Supplier: Avantor Fluid Handling

German precision engineered AODD pumps to get your application up and flowing.

Supplier: ELTEN

Metal- and leather-free ESD safety shoes made from microfibre upper with mesh inserts, a full padded bellows tongue and a dual-density PU/PU sole FUN.

Supplier: HARVARD APPARATUS

The CMA 470 refrigerated fraction collector is specifically designed to collect microliter volume fractions typical of microdialysates. It is a stand alone instrument, but it is equipped with a digital input/output port and an RS232 interface for connection to the software.

Supplier: Thermo Fisher Scientific

Slide-A-Lyzer MINI Dialysis devices, 3,5K MWCO, are disposable polypropylene cups with integrated, low-binding membranes for dialysis and high recovery of proteins and macromolecules >3,5 kDa in volumes from 10 µl to 2 ml. They were developed as a convenient means for dialysing small-volume samples of nucleic acids and proteins without undue sample loss. Low molecular weight contaminant removal, buffer exchange, desalting, equilibrium dialysis, micro conjugation reactions, and concentration can be accomplished with these devices.

Supplier: STEMCELL Technologies

The platelet-derived growth factor (PDGF) family has five heparin-binding members that assemble into four homodimers (PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD) and one heterodimer (PDGF-AB; Fretto et al.; Li and Eriksson). PDGF signals through the receptor tyrosine kinases PDGFRα and PDGFRβ. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al.). PDGF is a potent mitogen for cells of mesenchymal origin, such as fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto et al.; Sachinidis et al.). PDGF-BB is secreted by osteoblasts to induce mesenchymal stem cell migration and angiogenesis. It has also been shown that PDGF-BB is secreted by preosteoclasts during bone modeling and remodeling to induce angiogenesis and thus proper osteogenesis (Xie et al.).

Supplier: VWR Collection

The VWR® Advanced glove with polyurethane coating provides enhanced cut protection for a range of applications that would include a high risk of cuts.

Supplier: EP SCIENTIFIC

The EPA vials are ideal for water sample collection for volatile organic analysis. The vials with unbonded septa have a molded-in retainer ring to keep septa firmly in place while allowing septa to be removed and replaced as needed. Also there are vials with the septum permanently bonded to the cap for secure sealing.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a, antibody against human CD3, FITC-conjugated.