278 Résultats pour : "dedicating"

Supplier: Bioss

DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.

Supplier: Bioss

DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.

Supplier: Bioss

DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.

Supplier: TOSOH Bioscience

SkillPak™ BIO pre-packed columns are designed for a fast method development and scale-up of multi-column chromatography (MCC) or continuous chromatography processes. They are pre-packed with TOYOPEARL® process chromatography media for bioseparations.

Supplier: Cole Parmer

Shaker and incubator combination makes these devices ideal for cell culture procedures.

Supplier: Cole Parmer

Combine with a recirculating cooler for low-temperature applications.

Supplier: Bioss

DOCK 5 is a 1,870 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins. This cytoplasmic peripheral membrane protein activates Rac 1 and Rac 2 small GTPases, while presumably acting as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. DOCK 5 contains one DHR-1 (CZH-1) domain, one DHR-2 (CZH-2) domain and one SH3 domain. The DHR-2 domain is a putative GEF activity mediator. In mice, spontaneous mutation of the gene encoding DOCK 5 leads to deletion of the DHR-1 domain, which functions to bind phospholipids and assists in protein-protein interactions, resulting in rupture of lens cataract (RLC). Due to siRNA knockdown studies, it is suspected that DOCK 5 may also be an important mediator of CrkII/CrkL regulation of Caco-2 migration and spreading on COL4. There are two isoforms of DOCK 5 that exist as a result of alternative splicing events.

Supplier: Bioss

DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.

Supplier: Corning

The Corning® Step-R™ repeating pipettor is suitable to dispense volatile, dense, viscous, or foaming liquids, and for all applications where long dosing series are required. It works with eight syringe tips sizes to dispense doses from 1 μl upto 5 ml.

Supplier: Bioss

DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.

Supplier: PEAK SCIENTIFIC

The Precision Nitrogen 600 has been developed to provide a constant and consistent source of nitrogen for detector make-up gas at standard/typical detection levels for GC applications, as well as headspace vial pressurisation, purge and trap, tube conditioning for thermal desorption and sample preparation. These generators are capable of delivering high purity nitrogen, removing oxygen and moisture via Pressure Swing Adsorption and Carbon Molecular Sieve technology.

Supplier: Bioss

DOCK 5 is a 1,870 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins. This cytoplasmic peripheral membrane protein activates Rac 1 and Rac 2 small GTPases, while presumably acting as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. DOCK 5 contains one DHR-1 (CZH-1) domain, one DHR-2 (CZH-2) domain and one SH3 domain. The DHR-2 domain is a putative GEF activity mediator. In mice, spontaneous mutation of the gene encoding DOCK 5 leads to deletion of the DHR-1 domain, which functions to bind phospholipids and assists in protein-protein interactions, resulting in rupture of lens cataract (RLC). Due to siRNA knockdown studies, it is suspected that DOCK 5 may also be an important mediator of CrkII/CrkL regulation of Caco-2 migration and spreading on COL4. There are two isoforms of DOCK 5 that exist as a result of alternative splicing events.

Supplier: HAMILTON BONADUZ

The Microlab® 600 dispensers are highly precise syringe pumps with a touchscreen graphical user interface designed to quickly and easily dispense liquids. This positive displacement system provides better than 99% accuracy, independent of liquid viscosity, vapour pressure and temperature. The inert fluid path minimises sample carry over and improves compatibility with harsh chemicals. There are three different dispenser models available.

Supplier: PEAK SCIENTIFIC

Peak scientific’s Solaris XE nitrogen generator offers a reliable, compressor-free gas solution that can comfortably meet the demands of most mass spectrometers within Waters’ portfolio of instruments. Using our tried and tested membrane technology, Solaris XE can operate with varying flow rates (up to 35 L/min of high purity nitrogen), purity (up to 99,5%) and outlet pressure can be adjusted down from 8 bar.

Supplier: HICHROM

Kromasil® AmyCoat and CelluCoat are new generation polysaccharide based chiral phases which stretch the limits for chiral chromatography. High purity deactivated wide pore silica is coated with tris-(3,5-dimethylphenyl) carbamoyl functionalised amylose or cellulose selector.

Supplier: Thermo Fisher Scientific

Increase valuable laboratory storage space with CryoPlus™ Storage Systems, which store up to 38500 vials (2,0 ml). The ideal combination of liquid nitrogen, storage reliability and microprocessor technology, the CryoPlus series LN₂ storage system provides precise and accurate control over all parameters without complicated programming.

Supplier: HOSHIZAKI

Self contained cube ice makers producing high-quality cube ice. Meeting even the strictest hygiene requirements, this true allrounder offers many application possibilities in segments including the foodservice and medical sector.

Supplier: Thermo Orion

Use the Thermo Scientific™ Orion™ Star A series electrode holder with a meter-attached or swing arm electrode stand to organize your sensors for easier movement in and out of samples and simplified rinsing and storage. The electrode holder accepts up to six sensors using 12 mm holder with optional ATC probe insert, 20° angle holder for gas sensing ISEs, 15 mm holder for conductivity and DO probes, 12 mm flex clip holder for pH, ORP and ion selective electrodes, centre stirrer probe holder and removable RDO probe holder.

Supplier: Molecular Devices

The QPix® XE is a microbial colony picker ideal for labs with reduced space, but need efficient colony picking throughput. The QPix® XE is a great entry-level system to replace highly subjective and error prone manual picking with automated colony picking.

Supplier: LEICA MICROSYSTEMS

Mica - The world's first imaging Microhub. More than a highly automated microscope, Mica unites widefield and confocal imaging in a sample protecting, incubating environment. With the simple push of a button, you have everything you need - all in one place - to supercharge fluorescence imaging workflows and get meaningful scientific results faster.

Supplier: DWK Life Sciences

The WHEATON® OmniSpence® ELITE and UniSpense® PRO are intelligent peristaltic pumps for all dispensing needs. Whether the user is making sterile liquid transfers to and from containers or filling vials or titer plates these pumps will simplify and accelerate the laboratory throughput. It is ideal for any laboratory or clinical setting where accurate and precise liquid dispensing is important.

Supplier: EPPENDORF

Eppendorf Combitips® advanced, in 'Eppendorf Quality' grade, offer precise, positive displacement pipetting. Ideal for handling challenging liquids, ensuring accuracy and efficiency in diverse lab applications with their versatile and durable design.

Supplier: C LECTA

DENARASE® is a highly active endonuclease from Serratia marcescens. This enzyme is used in biopharmaceutical manufacturing to eliminate plasmid and host cell DNA/RNA. DENARASE® is manufactured under GMP conditions and is widely applied during the purification of viral vectors for gene/cell therapies and vaccines.

Supplier: Avantor Fluid Handling

Networking drives offer either native EtherNet/IP™ or Profibus communication-no additional hardware or firmware required.

Supplier: EPPENDORF

Eppendorf Combitips® advanced, individually blister-wrapped in 'Biopur®' grade, offer unparalleled purity for critical lab tasks, ensuring contamination-free, precise pipetting with an ergonomic design. Ideal for highly sensitive molecular biology applications.

Supplier: EPPENDORF

Eppendorf Combitips® advanced in 'PCR clean' grade offer superior positive displacement pipetting, ensuring precise handling of sensitive liquids in PCR and molecular biology, with contamination-free, ergonomic design for reliable lab results.

Supplier: VELP SCIENTIFIC

These cooled incubators have a refrigerated thermostat with 120 and 200 L capacity that ensures excellent connectivity, high performance in temperature control thanks to the innovative auto tuning.

Supplier: EPPENDORF

Eppendorf Combitips® advanced in 'Forensic DNA Grade' offer unmatched precision and safety, individually blister-wrapped for maximal DNA contamination prevention. Ideal for forensic applications requiring the utmost accuracy and sterility.

Supplier: EPPENDORF

Eppendorf Tubes® with screw cap are an ideal choice when working with medium-sized sample volumes (0,5 to 5,0 ml). SafeCode variants enhance sample identification, while the BioBased option, manufactured using renewable resources, provides an eco-friendly alternative without compromising performance.

Supplier: EBRO

Ces enregistreurs de données de température faciles à utiliser, dotés d'une connexion USB, surveillent la température et/ou l'humidité pendant le transport et le stockage de produits pharmaceutiques, médicaux ou d'autres denrées périssables, le transport de médicaments, de vaccins et de produits sanguins. Ils ne nécessitent aucune interface de programmation ou d'affichage de données. Un rapport au format PDF automatique peut être généré sans aucun logiciel.