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Anti-CD8A Mouse Monoclonal Antibody (APC (Allophycocyanin))/Cy7®) [clone: RPA-T8]

Anti-CD8A Mouse Monoclonal Antibody (APC (Allophycocyanin))/Cy7®) [clone: RPA-T8]

Supplier: Tonbo Biosciences

The RPA-T8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Expand 2 Items
 
Anti-CD8A Mouse Monoclonal Antibody (violetFluor® 450) [clone: RPA-T8]

Anti-CD8A Mouse Monoclonal Antibody (violetFluor® 450) [clone: RPA-T8]

Supplier: Tonbo Biosciences

The RPA-T8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Expand 2 Items
 
Anti-CD8 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: SK1]

Anti-CD8 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: SK1]

Supplier: Tonbo Biosciences

The SK1 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Expand 3 Items
 
Anti-CD8a Mouse Monoclonal Antibody (redFluor™ 710) [clone: RPA-T8]

Anti-CD8a Mouse Monoclonal Antibody (redFluor™ 710) [clone: RPA-T8]

Supplier: Tonbo Biosciences

The RPA-T8 antibody is specific for the 32 to 34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Expand 2 Items
 
Anti-CD8 Mouse Monoclonal Antibody (APC (Allophycocyanine)) [clone: SK1]

Anti-CD8 Mouse Monoclonal Antibody (APC (Allophycocyanine)) [clone: SK1]

Supplier: Tonbo Biosciences

The SK1 antibody is specific for the 32 to 34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Expand 3 Items
 
Anti-CD8A Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: RPA-T8]

Anti-CD8A Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: RPA-T8]

Supplier: Tonbo Biosciences

The RPA-T8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Expand 3 Items
 
Anti-CD8A Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: RPA-T8]

Anti-CD8A Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: RPA-T8]

Supplier: Tonbo Biosciences

The RPA-T8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Expand 3 Items
 
Anti-CD8A Mouse Monoclonal Antibody (FITC (Fluorescein)) [clone: RPA-T8]

Anti-CD8A Mouse Monoclonal Antibody (FITC (Fluorescein)) [clone: RPA-T8]

Supplier: Tonbo Biosciences

The RPA-T8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Expand 3 Items
 
Anti-CD8A Mouse Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: RPA-T8]

Anti-CD8A Mouse Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: RPA-T8]

Supplier: Tonbo Biosciences

The RPA-T8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Expand 2 Items
 

Anti-TNFRSF8 Mouse Monoclonal Antibody [clone: Ber-H2] (FITC (Fluorescein Isothiocyanate))

Supplier: ProSci Inc.

The Ber-H2 monoclonal antibody specifically reacts with human CD30, a 120 kDa type I transmembrane glycoprotein of the tumor necrosis factor receptor superfamily (TNFR) also known as the Ki-1 antigen. CD30 can elicit signals leading to either activation or apoptosis through interaction with CD30 ligand (CD30L). It is expressed by a subset of extrafollicular activated B and T cells, lung macrophages, activated NK cells, lymphomas, and endothelial cells. It is highly expressed on Hodgkins and Reed-Sternberg cells.

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Anti-TNFRSF8 Mouse Monoclonal Antibody [clone: Ber-H2] (PE (Phycoerythrin))

Supplier: ProSci Inc.

The Ber-H2 monoclonal antibody specifically reacts with human CD30, a 120 kDa type I transmembrane glycoprotein of the tumor necrosis factor receptor superfamily (TNFR) also known as the Ki-1 antigen. CD30 can elicit signals leading to either activation or apoptosis through interaction with CD30 ligand (CD30L). It is expressed by a subset of extrafollicular activated B and T cells, lung macrophages, activated NK cells, lymphomas, and endothelial cells. It is highly expressed on Hodgkins and Reed-Sternberg cells.

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Anti-KIT Mouse Monoclonal Antibody [clone: YB5.B8] (PE (Phycoerythrin))

Supplier: ProSci Inc.

The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDa receptor for stem cell factor (SCF) or steel factor. This tyrosine kinase protein is expressed mainly on hematopoietic progenitor, mast cells, acute myeloid leukemia cells (AML). CD117 activation promotes proliferation and cell differentiation on these cell subtypes. A lack or defect of SCF can lead to a decrease in number of hematopoietic progenitor cells and severe anemia.

Expand 1 Items
 

Anti-TNFRSF8 Mouse Monoclonal Antibody [clone: Ber-H2] (PE (Phycoerythrin))

Supplier: ProSci Inc.

The Ber-H2 monoclonal antibody specifically reacts with human CD30, a 120 kDa type I transmembrane glycoprotein of the tumor necrosis factor receptor superfamily (TNFR) also known as the Ki-1 antigen. CD30 can elicit signals leading to either activation or apoptosis through interaction with CD30 ligand (CD30L). It is expressed by a subset of extrafollicular activated B and T cells, lung macrophages, activated NK cells, lymphomas, and endothelial cells. It is highly expressed on Hodgkins and Reed-Sternberg cells.

Expand 1 Items
 

Anti-TNFRSF8 Mouse Monoclonal Antibody [clone: Ber-H2] (FITC (Fluorescein Isothiocyanate))

Supplier: ProSci Inc.

The Ber-H2 monoclonal antibody specifically reacts with human CD30, a 120 kDa type I transmembrane glycoprotein of the tumor necrosis factor receptor superfamily (TNFR) also known as the Ki-1 antigen. CD30 can elicit signals leading to either activation or apoptosis through interaction with CD30 ligand (CD30L). It is expressed by a subset of extrafollicular activated B and T cells, lung macrophages, activated NK cells, lymphomas, and endothelial cells. It is highly expressed on Hodgkins and Reed-Sternberg cells.

Expand 1 Items
 

Anti-KIT Mouse Monoclonal Antibody [clone: YB5.B8] (PE (Phycoerythrin))

Supplier: ProSci Inc.

The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDa receptor for stem cell factor (SCF) or steel factor. This tyrosine kinase protein is expressed mainly on hematopoietic progenitor, mast cells, acute myeloid leukemia cells (AML). CD117 activation promotes proliferation and cell differentiation on these cell subtypes. A lack or defect of SCF can lead to a decrease in number of hematopoietic progenitor cells and severe anemia.

Expand 1 Items
 

Papier indicateur, acétate de plomb (II), Supelco®

Supplier: Merck

Le papier d'acétate de plomb (II) est utilisé pour la détermination de la teneur en sulfure et hydrogène sulfuré.

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