2778 Résultats pour : "STEMCELL Technologies"

Supplier: STEMCELL Technologies

Serum-free medium kit for highly efficient SMAD inhibition-mediated neural induction of human ES and iPS cells.

Supplier: STEMCELL Technologies

Defined cell culture medium for expansion of reset naïve human embryonic stem (ES) and induced pluripotent stem (iPS) cells.

Supplier: STEMCELL Technologies

Defined medium kit for transgene-free induction of reset naïve human pluripotent stem cells - 1 Kit

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of human cells labeled with PE-conjugated antibodies.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of human cells labeled with FITC-conjugated antibodies.

Supplier: STEMCELL Technologies

Column-free immunomagnetic positive selection of human CD66b+ cells for HLA analysis.

Supplier: STEMCELL Technologies

The EBV (EBNA-1) Peptide pool is a lyophilised mixture of 158 peptides from Epstein-Barr nuclear antigen 1 (EBNA-1) of Epstein-Barr virus (EBV; strain B95-8). EBNA-1 plays a critical role in the stable latent infection by EBV and may contribute to the survival of EBV-infected cells through its interaction with ubiquitin carboxyl-terminal hydrolase 7 (USP7). The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 641 on EBNA-1.

Supplier: STEMCELL Technologies

The CMV (pp65) peptide pool is a lyophilised mixture of 138 peptides from the 65 kDa phosphoprotein (pp65) of human cytomegalovirus (CMV; strain AD169). pp65 has been shown to counteract the induction of interferon response by preventing the activation of interferon response factor 3 (IRF-3). pp65 is also important in inducing transcription of viral immediate-early promoter. The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 561 on pp65.

Supplier: STEMCELL Technologies

Cell culture medium kit for robust generation of ventral forebrain neural organoids from human pluripotent stem cells.

Supplier: STEMCELL Technologies

The SARS-CoV-2 (VME1) peptide pool is a lyophilised mixture of 53 peptides from the SARS-CoV-2 membrane protein VME1. VME1 is a structural protein that is common to all coronaviruses, and it plays a critical role in viral assembly. The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 222 on VME1.

Supplier: STEMCELL Technologies

The SARS-CoV-2 (spike protein) peptide pool is provided as two lyophilised mixtures (subpools) from the SARS-CoV-2 spike protein. Each subpool contains 158 peptides, for a total of 316 peptides. The virus attaches to the cell membrane of the host through the interaction between spike protein and angiotensin-converting enzyme 2 (ACE2) receptor, and the spike protein plays a critical role in viral entry. The subpools consist of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 1273 on the spike protein.

Supplier: STEMCELL Technologies

Supplement for the differentiation of mouse naïve CD4+ T cells into Th2 cells.

Supplier: STEMCELL Technologies

Immunomagnetic negative selection kit.

Supplier: STEMCELL Technologies

Column-free immunomagnetic positive selection of human B cells for HLA analysis.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of human CD33+ and CD66+ cells (e.g. myeloid cells).

Supplier: STEMCELL Technologies

R-Spondin-1 (RSPO1) is the prototype member of the R-Spondin (RSPO) protein subfamily of a superfamily of thrombospondin type 1 repeat (TSR-1)-containing proteins (Chen et al.; Kamata et al.; Kazanskaya et al.; Kim et al.). Although unable to initialize signaling, RSPO family members are potent enhancers of WNT signaling (Cruciat and Niehrs; de Lau et al.; Kamata et al.; Kazanskaya et al.). They are characterized by a TSR-1 domain, a carboxy-terminal region with positively charged amino acids, and two N-terminal furin-like cysteine-rich repeats (Glinka et al.; Kazanskaya et al.). R­-Spondin-1 activates β­-catenin signaling via the WNT signaling cascade and by indirectly increasing low-density lipoprotein receptor-related protein 6 (LRP6) on the cell surface. It does this by binding leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5), and competing with WNT antagonist DKK­1 for binding to the WNT co­receptors, Kremen and LRP­6, which reduces DKK­1-­mediated internalization of LRP6 (Binnerts et al.). RSPO1 is involved in a wide range of pleiotropic roles during embryogenesis, it is required for the specification of hematopoietic stem cells, and it has been shown to be important in the growth, survival, and migration of ovarian cancer cells (Cruciat and Niehrs; de Lau et al.; Genthe and Clements; Liu et al.).

Supplier: STEMCELL Technologies

Bone morphogenetic protein 4 (BMP-4) is a member of the highly conserved transforming growth factor β (TGF-β) superfamily. Mature BMP-4 is a disulfide-linked homodimeric protein consisting of two 116-amino-acid residue subunits, and is generated by the proteolytic removal of the signal peptide and propeptides (Xiao et al.). BMP-4 binds to type I and type II receptors on cells. This binding results in the phosphorylation of receptor 1, which in turn results in the phosphorylation of Smad proteins, which then go on to act as transcription factors (Zhang et al.). BMPs have been shown to be key regulators of embryogenesis and are known to play a role in the growth and differentiation of various cell types, including embryonic stem (ES) cells, induced pluripotent stem (iPS) cells, mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells (Chadwick et al.; Graham et al.; Jones et al.; Lengerke et al.; Zhang et al.).

Supplier: STEMCELL Technologies

Receptor activator of nuclear factor kappa-B ligand (RANKL) is a member of the tumor necrosis factor (TNF) superfamily (Anderson et al.). Cytokines in the TNF superfamily are involved in a variety of long-term cellular activities such as differentiation, proliferation, and cell death (MacEwan). RANKL is a type II homotrimeric transmembrane protein expressed in both a membrane-bound and secreted form (Ikeda et al.). RANKL binds to the receptor activator of nuclear factor kappa-B (RANK). Upon binding to its receptor, RANKL activates the AKT signaling pathway (Moon et al.). Osteoprotegerin (OPG) may also bind RANKL, and this binding competes with RANKL-RANK binding (Lacey et al.). RANKL is involved in osteoclastogenesis (Lacey et al.; Yasuda et al.) and T cell activation (Wong et al.).

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2b antibody against human, rhesus, cynomolgus CD32, FITC-conjugated.

Supplier: STEMCELL Technologies

Rat (WI) monoclonal IgG2b antibody against mouse TER119.

Supplier: STEMCELL Technologies

Xeno-free and serum-free medium for culture and expansion of human hematopoietic cells.

Supplier: STEMCELL Technologies

Serum- and BPE-free medium for human small airway epithelial cells cultured at the air-liquid interface.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of particle-free mouse cells labeled with APC-conjugated antibodies.

Supplier: STEMCELL Technologies

Culture medium kit for establishment and maturation of human cerebral organoids.

Supplier: STEMCELL Technologies

For detection and measurement of human immunoglobulin E.

Supplier: STEMCELL Technologies

Serum-free media for generation and maturation of branching lung organoids from human ES and iPS cells.

Supplier: STEMCELL Technologies

For differentiation of human ES or iPS cells into erythroid progenitor cells.

Supplier: STEMCELL Technologies

A cellular protein for detection of apoptotic cells, APC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a, antibody against human CD3, FITC-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG1, antibody against mouse IFN-gamma, PE-conjugated.