2778 Résultats pour : "STEMCELL Technologies"

Supplier: STEMCELL Technologies

FRET-based peptide substrate for detection of protease activity of coronaviruses - 1000 tests.

Supplier: STEMCELL Technologies

Differentiation kit for the generation of midbrain neuronal precursors from human ES and iPS cell-derived neural progenitor cells.

Supplier: STEMCELL Technologies

Mouse monoclonal antibody against human, rhesus, cynomolgus CD81, unconjugated.

Supplier: STEMCELL Technologies

Fluorescent dye conjugates for staining cell membranes of gram-positive bacteria, mammalian cells, and yeast bud scars - 1000 µg.

Supplier: STEMCELL Technologies

Fluorescent dye conjugates for staining cell membranes of gram-positive bacteria, mammalian cells, and yeast bud scars - 1000 µg.

Supplier: STEMCELL Technologies

Green fluorescent lipophilic dye for staining cell membranes and other hydrophobic structures in live and fixed cells

Supplier: STEMCELL Technologies

For staining cell plasma membranes in fixed cells - 500 tests.

Supplier: STEMCELL Technologies

For the in vitro differentiation of mouse MSCs, ADSCs, and MEFs into adipocytes.

Supplier: STEMCELL Technologies

Reprogramming medium for human iPS cell induction.

Supplier: STEMCELL Technologies

Feeder-free and animal component-free reprogramming medium for human iPS cell induction.

Supplier: STEMCELL Technologies

Hybridoma expansion medium with hypoxanthine and thymidine (animal origin-free).

Supplier: STEMCELL Technologies

Medium and Transwell® inserts for human airway epithelial cells cultured at the air-liquid interface.

Supplier: STEMCELL Technologies

Culture medium kit for initiation of human pancreatic organoids.

Supplier: STEMCELL Technologies

Cell culture kit for establishment of hPSC-derived neural crest cells.

Supplier: STEMCELL Technologies

Serum-free medium for culture and expansion of hematopoietic cells.

Supplier: STEMCELL Technologies

Betacellulin is a member of the epidermal growth factor (EGF) family, and signals through EGF receptor and ERBB4. It activates ERK and AKT pathways, which induces neural stem cell proliferation and prevents spontaneous differentiation in culture. Betacellulin stimulates the expansion of neural stem cells, transit-amplifying cells, and neuroblasts derived from subventricular zone and dentate gyrus (Gómez-Gaviro et al.). It is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin down-regulates E-cadherin expression in ovarian cancer cell lines via MEK/ERK1/2 and PI3K/AKT signaling pathways, thus increasing cell migration (Zhao et al.). It is a modulator of interferon (IFN) response and enhances anti-viral effects of IFN (Al-Yahya et al.). Betacellulin is expressed in pancreatic α cells, β cells, and duct cells. It induces the proliferation of pancreatic cancer cell lines, inhibits apoptosis, promotes the neogenesis of β cells, and converts non-β cells into insulin-producing cells (Kawaguchi et al.; Miyagawa al.; Saito et al.).

Supplier: STEMCELL Technologies

GRO (growth-regulated oncogene)-beta or CXCL2 is a member of the CXC family, which plays an integral role in recruitment and activation of neutrophils and basophils in response to tissue injury and microbial infection. GRO-beta and GRO-gamma are closely related to GRO-alpha and share 90% and 86% amino acid sequence homology, respectively, with GRO-alpha. Receptor-binding studies have demonstrated that GRO-alpha, -beta, and -gamma signal mainly through G protein-coupled receptors CXCR1 and CXCR2 (Ahuja and Murphy). GRO-beta is expressed in epithelial cells, monocytes, fibroblasts, and melanocytes and is further induced during inflammatory, epithelialization, and angiogenic processes, for example during the wound healing process of human burn wounds (Zaja-Milatovic and Richmond). GRO-beta also stimulates mitogenesis in certain human melanoma cells (Unemori et al.).

Supplier: STEMCELL Technologies

Amphiregulin is a member of the epidermal growth factor (EGF) family. It binds to several receptors including EGFR/ErbB1, HER2/ErbB2, HER3/ErbB3, and HER4/ErbB4, which activates Ras/Raf/MAPK and PI3K/AKT pathways. This results in cell proliferation, apoptosis resistance, and invasive behaviour (Normanno et al.). The expression of amphiregulin is induced by tissue injury and inflammation. Amphiregulin promotes mammary development, trophoblast growth, lung and kidney branching morphogenesis, and keratinocyte proliferation. It stimulates the growth of most cell types, including normal and transformed mammary epithelial cells, and malignant cells of the colon, prostate, cervix, and pancreas (Berasain and Avila).

Supplier: STEMCELL Technologies

Vascular endothelial growth factor (VEGF-121) is a naturally-occurring VEGF-A splice variant involved in embryonic vasculogenesis and angiogenesis. VEGF binds to VEGFR-1 and VEGFR-2, and activates Raf/MEK/ERK and PI3K/AKT pathways. VEGF-121 is released as a freely diffusible protein by a variety of normal and transformed cells. It plays an important role in neurogenesis both in vitro and in vivo (Storkebaum et al.). It has neurotrophic effects on neurons of the central nervous system and promotes growth and survival of dopaminergic neurons and astrocytes. VEGF also promotes growth and survival of vascular endothelial cells, monocyte chemotaxis, and colony formation by granulocyte-macrophage progenitor cells (Ferrara et al.).

Supplier: STEMCELL Technologies

TRAIL (TNF-related apoptosis-inducing ligand) belongs to the tumor necrosis factor (TNF) superfamily and is associated with initiating apoptosis. TRAIL has four major receptors: two death receptors DR4 and DR5, and two decoy receptors DcR1 and DcR2. TRAIL binds to the death receptors, which recruits the Fas-associated death domain (FADD) and activates caspases 8 and 10, which eventually leads to apoptosis (Pitti et al.; Wiley et al.; Zauli and Secchiero). It has been shown that mice lacking the expression of TRAIL have defects in thymocyte apoptosis and negative selection, and these mice had increased susceptibility to autoimmune diseases (Lamhamedi-Cherradi et al.).

Supplier: STEMCELL Technologies

Cell culture medium for establishment and maintenance of mouse pancreatic exocrine organoids.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human naïve CD4+ T cells.

Supplier: STEMCELL Technologies

Serum-free medium kit for highly efficient SMAD inhibition-mediated neural induction of human ES and iPS cells.

Supplier: STEMCELL Technologies

Defined cell culture medium for expansion of reset naïve human embryonic stem (ES) and induced pluripotent stem (iPS) cells.

Supplier: STEMCELL Technologies

Defined medium kit for transgene-free induction of reset naïve human pluripotent stem cells - 1 Kit

Supplier: STEMCELL Technologies

Animal component-free, defined cryopreservation medium with 10% DMSO.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched mouse pan-naïve T cells

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD138 (syndecan-1), APC-conjugated.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human CD4+ T cells.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched non-human primate T cells