"RAYPA"

Supplier: US Biological

Anti-GABPA Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-RAD9A Rabbit Polyclonal Antibody

Supplier: Bioss

Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localisation to microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.

Supplier: Aviva Systems Biology

Anti-RAP1A Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences

Rap1, which is a member of the Ras family of GTP-binding proteins, cycles between an active GTP-bound and an unactive GDP-bound form that is mediated by GTPase activating protein (GAP). Rap1 is proposed to regulate Ras-mediated signaling and may also be involved in the regulation of Integrin-mediated cell adhesion although the mechanism of regulation is not known.

Supplier: US Biological

Anti-RAMP2 Sheep Polyclonal Antibody

Supplier: US Biological

Anti-RAD9A Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-RAMP1 Sheep Polyclonal Antibody

Supplier: US Biological

Anti-RAB6A Rabbit Polyclonal Antibody

Supplier: Aviva Systems Biology

Anti-RAD9A Rabbit Polyclonal Antibody

Supplier: Abgent

Anti-RAD9 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-RAMP2 Sheep Polyclonal Antibody

Supplier: Enzo Life Sciences

The Ras superfamily of small guanosine triphosphatases (GTPases) is traditionally subdivided into five families: Ras, Rho, Rab, Ran, and Arf. Rap1/Krev1 is a member of the Ras family of low molecular weight GTP-binding proteins1. Ras-like GTPases are ubiquitously expressed, evolutionarily conserved molecular switches that couple extracellular signals to various cellular responses. Rap1 is primarily found at the cytosolic side of intracellular membranes and has two isoforms: Rap1a and 1b2. Both isoforms have a molecular mass of 21 kDa and are isoprenylated at the carboxyl-terminal and phosphorylated by the cAMP-dependent protein kinase A (PKA)3. Rap1 cycles between a GTP-bound active form and a GDP-bound inactive form that is mediated by GTPase activating protein (GAP) and GDP dissociation stimulator (GDS)4,5. Activation occurs by a variety of extracellular stimuli through several conserved guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs). Rap1 is proposed to regulate Ras mediated signaling and may also be involved in the regulation of integrinmediated cell adhesion, although the mechanism of regulation is not known. Overexpression of Rap reverses the transformed phenotype induced by Ras, possibly by competing with Ras for interaction with Ras-GAP. Rap has been shown to participate in MAP kinase cascade activated by growth factor and maintaining human T cell anergic state by blocking IL-2 expression.

Supplier: US Biological

Anti-RAD9A Rabbit Polyclonal Antibody

Supplier: Aviva Systems Biology

Anti-GABPA Rabbit Polyclonal Antibody

Supplier: Abcam

Recombinant Human RAMP3 protein is a Human Fragment protein, in the 24 to 118 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.