12531 Résultats pour : "Enzo Life Sciences"

Supplier: Enzo Life Sciences

Antioxidant. SIRT1 activator.

Supplier: Enzo Life Sciences

Produced in E. coli. The extracellular domain of human CD40L (CD154) (aa 116-261) is fused at the N-terminus to a linker peptide (6 aa) and a FLAG®-tag.

Supplier: Enzo Life Sciences

Produced in HEK 293 cells. Secreted from the cells using a proprietary signal peptide. Full length extracellular human Nampt (visfatin/PBEF) (aa 1-491) is fused at the N-terminus to a FLAG®-tag.

Supplier: Enzo Life Sciences

The Screen-Well® myotoxicity library is a focused collection of 60 compounds with defined and diverse myotoxicity, including rhabdomyolysis, cardiomyopathy, mitrochondrial myopathy, vacuolar myopathy, and more. A variety of structurally and mechanistically different compound classes are included, as well as non toxic controls. All compounds are dissolved in DMSO at 10 mM unless otherwise stated in the documentation provided with the library. Selected compounds are dissolved in DI water. All compounds are provided at 100 µl volumes in a 96-Well plate.

Supplier: Enzo Life Sciences

Mouse-HRP/rabbit-AP IHC is a biotin-free one-step detection system suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and cryostat sections.

Supplier: Enzo Life Sciences

Immunohistochemistry (mouse/rabbit-HRP) detection reagent is a non-biotin one-step detection reagent.

Supplier: Enzo Life Sciences

The IHC PAP pen provides a hydrophobic barrier when a circle is drawn around a specimen on a glass slide.

Supplier: Enzo Life Sciences

LRRC32 (leucine rich repeat containing 32; also known as GARP or Garpin; Glycoprotein A repetitions predominant) is a glycoprotein expressed on the cell surface of megakaryocytes, platelets and activated regulatory T (Treg) cells.

Supplier: ENZO LIFE SCIENCES

Na⁺/K⁺ ATPase inhibitor

Supplier: ENZO LIFE SCIENCES

Anti-inflammatory and immunosuppressive

Supplier: ENZO LIFE SCIENCES

Glucoside of daidzein.

Supplier: ENZO LIFE SCIENCES

Potent antitumor agent. Inhibitor of DNA-topoisomerase. Analog of (S)-(⁺)-camptothecin. Used in chemotherapy of several different cancers.

Supplier: ENZO LIFE SCIENCES

Inhibitor of protein phosphatase.

Supplier: ENZO LIFE SCIENCES

ACAT2 inhibitor

Supplier: ENZO LIFE SCIENCES

Cyclic tetrapeptide. Inhibitor of chloroplast F1-ATPase (CF1). Does not inhibit the homologous enzymes from chloroplasts of insusceptible plant species or from bacteria or mitochondria.

Supplier: ENZO LIFE SCIENCES

Microcystins are a group of cyclic heptapeptide hepatotoxins produced by a number of cyanobacterial genera. The most notable of which, and namesake, is the widespread genus Microcystis. Structurally, all microcystins consist of the generalized structure cyclo(-D-Ala1-X2-D-MeAsp3-Y4-Adda5-D-Glu6-Mdha7-). X and Y are variable L-amino acids, D-MeAsp is D-erythro-β-methylaspartic acid and Mdha is N-methyldehydroalanine. Adda is the cyanobacteria unique C20 β-amino acid 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoic acid. Substitutions of the variable L-amino acids at positions 2 and 4 give rise to at least 21 known primary microcystin analogs and alterations in the other constituent amino acids result in more than 90 reported mycrocystins to date.

Supplier: ENZO LIFE SCIENCES

Carciogenesis inhibitor

Supplier: ENZO LIFE SCIENCES

Analog of microcystin-LR (Prod. No. ALX-350-012) with Tyr substituted in place of Arg.

Supplier: ENZO LIFE SCIENCES

Inhibits platelet aggregation. DNA polymerase inhibitor. Shows antifungal activity.

Supplier: ENZO LIFE SCIENCES

TdT inhibitor

Supplier: ENZO LIFE SCIENCES

Precursor of the highly toxic cyclic pentapeptide, nodularin.

Supplier: ENZO LIFE SCIENCES

Antibiotic which suppresses nitric oxide (NO) toxicity in pancreatic islet cells. Inhibits protein synthesis by inhibition of elongation factor G at the level of the ribosome.

Supplier: ENZO LIFE SCIENCES

Immunosuppressant.

Supplier: ENZO LIFE SCIENCES

F-ATPase inhibitor.

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Phomopsin A ≥98% (par HPLC)

Supplier: ENZO LIFE SCIENCES

Triterpenoid. Antitumor agent. Induces caspase-dependent apoptosis by inhibiting the chymotrypsin-like activity of the proteasome. Inhibits NF-κB activation via inhibition of IKKα or IKKβ. Inhibits induction of inducible nitric oxide synthase (iNOS; NOS II). Shows in vitro antimalarial and insecticidal activity. Induces mitochondrial cell death. Has antiproliferative, antifungal and antiviral properties. Potent and reversible monoacylglycerol lipase (MGL) inhibitor.

Supplier: ENZO LIFE SCIENCES

PKC activator.

Supplier: ENZO LIFE SCIENCES

Protein synthesis inhibitor

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Antitumor antibiotic. Catalytic inhibitor of topoisomerase II. Strong protein phosphatase 2A (PP2A) inhibitor (IC50=3.2nM). Weak inhibitor for PP1 (IC50=131µM). No apparent effect on PP2B. The binding site for fostriecin on PP2A is different from that of okadaic acid.

Supplier: ENZO LIFE SCIENCES

Co-metabolite of nemadectin. Antitumor agent with weak antifungal and nematocidal activity.