320 Résultats pour : "Charles River Laboratories Cell Solutions"

Supplier: Charles River Laboratories Cell Solutions

Naive T cells are isolated by depleting CD45RO^₊ cells via immunomagnetic bead separation from a freshly collected leukopheresis product. Naive T cells are phenotypically classified as CD45⁺, CD^₊, and CD45RA^₊.

Supplier: Charles River Laboratories Cell Solutions

CD8⁺ cytotoxic T cells are isolated from mononuclear cells by positive selection using immunomagnetic cell separation procedures.

Supplier: Charles River Laboratories Cell Solutions

CD4⁺/CD25⁺ regulatory T cells were isolated from leukapheresis product by CD127 depletion and positive selection using CD25 immunomagnetic beads. Peripheral blood cells are collected from normal human volunteers by direct collection or by using the COBE® Spectra or Spectra Optia® Apheresis System where cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.

Supplier: Charles River Laboratories Cell Solutions

Human mononuclear cells are isolated from IRB-consented volunteer donors diagnosed with HIV or AIDS.

Supplier: Charles River Laboratories Cell Solutions

Mononuclear cells used for researching the causes, diagnosis, supportive care and treatment of Diabetes Mellitus 2 (DM2), the most common form of diabetes. Human mononuclear cells are collected from human volunteer donors diagnosed with DM2 under IRB approved informed consent by whole blood or leukapheresis using the COBE® Spectra Apheresis System MNC collection protocol.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of Crohn's disease (CD). Collected from IRB-consented donors diagnosed with CD.

Supplier: Charles River Laboratories Cell Solutions

Human mononuclear cells, rheumatoid arthritis (RA)

Supplier: Charles River Laboratories Cell Solutions

Human serum, systemic lupus erythematosus (SLE)

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood M2 macrophages are derived from purified monocytes. CD14⁺ monocytes were positively selected via immunomagnetic beads and were cultured in the presence of M-CSF for 10 days. The M2 phenotyping was confirmed by morphology and the expression of specific biomarkers which monitored by flow cytometry. The cells were harvested after 10 days of in vitro culture.

Supplier: Charles River Laboratories Cell Solutions

Human mononuclear cells, multiple myeloma

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Human serum, chronic lymphocytic leukemia (CLL)

Supplier: Charles River Laboratories Cell Solutions

CD34⁺ cells are isolated using positive immunomagnetic cell separation procedures from umbilical cord blood. Human cord blood is collected aseptically at the time of delivery from healthy pregnant women under institutional review board (IRB) approved procedures.

Supplier: Charles River Laboratories Cell Solutions

CD34 depleted mononuclear cells from mobilised peripheral blood are isolated by depleting the CD34 cells using immunomagnetic anti-CD34 microbeads.

Supplier: Charles River Laboratories Cell Solutions

Ulcerative colitis (UC) is isolated from mononuclear cells collected from IRB-consented donors diagnosed with ulcerative colitis (UC).

Supplier: Charles River Laboratories Cell Solutions

Bone marrow is a major source of stem cells, which are being used in cancer research, cell studies, transplantation studies, and other research.

Supplier: Charles River Laboratories Cell Solutions

Mesenchymal stem cells (MSC) are cultured from freshly collected adult human bone marrow. MSCs are isolated by adherence from bone marrow mononuclear cells, isolated using a density gradient. Adherent cells were cultured in MEM-alpha, supplemented with L-glutamine and Human Platelet Lysate. Bone marrow aspirate is collected from healthy human volunteer donors under IRB approved informed consent and drawn from the posterior iliac crest using a syringe containing anticoagulant.

Supplier: Charles River Laboratories Cell Solutions

HypoThermosol® biopreservation media is a novel, engineered, optimised hypothermic storage and shipping media product. Serum-free, protein-free HypoThermosol® is designed to provide maximum storage and shipping stability for biologics at 2 to 8 °C.

Supplier: Charles River Laboratories Cell Solutions

Human serum used for researching the causes, diagnosis, supportive care and treatment of herpes simplex virus 2 (HSV 2). Collected from IRB-consented donors diagnosed with HSV 2.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of prostate cancer (PC), the most common type of cancer in men. Collected from IRB-consented donors diagnosed with PC.

Supplier: Charles River Laboratories Cell Solutions

Human plasma, multiple myeloma (MM)

Supplier: Charles River Laboratories Cell Solutions

AAV1/2 Vector with CMV promoter, human A53T alpha-synuclein, WPRE, bovine growth hormone (BGH), and polyadenylation sequence.

Supplier: Charles River Laboratories Cell Solutions

M1 and M 2 macrophages are derived from purified CD14⁺ monocytes. CD14⁺ monocytes were positively selected via immunomagnetic beads and were cultured in the presence of GM-CSF(M1) or M-CSF(M2) for 10 days. The phenotyping was confirmed by morphology and the expression of specific biomarkers.

Supplier: Charles River Laboratories Cell Solutions

CD19⁺ B cells are isolated from mononuclear cells by positive or negative selection using immunomagnetic cell separation procedures. Peripheral blood cells are collected from normal human volunteers by direct collection or by using the COBE® Spectra or Spectra Optia® Apheresis System where cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.

Supplier: Charles River Laboratories Cell Solutions

Naive CD4⁺ T cells are isolated from mononuclear cells by positive selection using immunomagnetic cell separation procedures.

Supplier: Charles River Laboratories Cell Solutions

Peripheral blood mononuclear cells (PBMC) are isolated from blood collected in FDA-registered collection centres, from IRB consented healthy human donors and following cGMP and cGTP collection guidelines.

Supplier: Charles River Laboratories Cell Solutions

A Leukopak is an enriched leukapheresis product collected from normal peripheral blood. It is composed of a variety of blood cells including monocytes, lymphocytes, platelets, plasma, and red cells. A leukopak contains a higher concentration of cells as compared to standard venipuncture collection methods or buffy coat products.

Supplier: Charles River Laboratories Cell Solutions

Human mononuclear cells, colorectal cancer (CRC)

Supplier: Charles River Laboratories Cell Solutions

Plasma used for researching the causes, diagnosis, supportive care and treatment of acute myeloid leukemia (AML). Collected from IRB-consented volunteer donors blood diagnosed with acute myeloid leukemia (AML).

Supplier: Charles River Laboratories Cell Solutions

Human serum used for researching the causes, diagnosis, supportive care and treatment of colorectal cancer (CRC). Collected from IRB-consented donors diagnosed with CRC.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of hepatitis C virus (HCV). Collected from IRB-consented donors diagnosed with HCV.