J.T.Baker® Cell Lysis Solution, Biotech Reagent

J.T.Baker® Cell Lysis Solution Biotech Reagent is a cGMP pre-formulated and ready to use detergent optimized for the extraction and recovery of AAV particles from producer cell lines (HEK293 parental and suspension lines, SF9). J.T.Baker® Cell Lysis Solution is a proprietary blend of nonionic surfactants, free of octyl phenol ethoxylate, which demonstrates comparable performance industry standard detergents while addressing environmental concerns associated with REACH and downstream clearance concerns. Designed for Gene Therapy workflows, this formulation is easy to use and handle as it is ready-to-use, has low viscosity, does not require cold temperature shipping or storage, and is available in sizes to support processes from development to large scale commercial batches. Detail description provided in technical literature.

• Comparable cell lysis performance to octyl phenol ethoxylate
• Improved protection of viral particles
• Easy to use and handle due to reduced foaming and viscosity and Room Termperature shipping and storage
• 0.1 µm filtered solution

Proprietary formulation. Not hazardous according to regulation 29 CFR 1910.1200 (OSHA HCS)

Chemical Specifications of GMP Cell lysis solution:
GMP Manufactured Product
Refractive Index: 1.1-1.5
Appearance: Passes Test
pH : For information only
Viscosity (25°C) : For information only
Density: 0.9 – 1.2 g/mL
Total Aerobic Microbial Count: 100 cfu/mL
Total Yeast and Mold Count: 10 cfu/mL
UV-Vis (max Absorption) at 380-450 nm: For information only

Chemical Specifications of GMP Cell lysis solution
GMP Manufactured Product
Refractive Index: 1.1-1.5
Appearance: Passes Test
pH: For information only
Viscosity (25°C): For information only
Density: 0.9 – 1.2 g/mL
Total Aerobic Microbial Count: 100 cfu/mL
Total Yeast and Mold Count: 10 cfu/mL
UV-Vis (max Absorption) at 380-450 nm: For information only