Anti-Ym1 Rabbit Polyclonal Antibody

Catalog # STMC60130

Supplier: STEMCELL Technologies

Catalog # STMC60130

Supplier: STEMCELL Technologies

Specifications

Nom de l'antigène:
Ym1
Clonalité:
Polyclonal
Conjugaison:
Unconjugated
Hôte:
Rabbit
Isotype:
IgG
Réactivité:
Mouse
ID de gène:
12655
Taille:
300 μl
Cdt:
0,3 mL

Specifications

About this item

Rabbit polyclonal IgG antibody against mouse Ym1, unconjugated.

Ym1 is an ~45 kDa secreted protein synthesized by activated mouse peritoneal macrophages during the inflammatory response elicited by parasitic infections. Ym1 is a granule protein in neutrophils and has been purified from eosinophilic crystals that form in the bronchoalveolar lavage fluid of mev/mev and SHIP (SH2-containing inositol 5’ phosphatase) knockout mice. The eosinophilic crystals formed in mice are considered to be histologically identical to the Charcot-Leyden crystals found in humans. Ym1 is homologous to T lymphocyte-derived eosinophil chemotactic factor (ECF-L) but elicits only a weak chemotactic response in eosinophils. Ym1 binds to heparin, GlcN oligomers and heparan sulfate. It belongs to a protein family related to chitinases but does not possess chitinase activity.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: Ym1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse