Anti-CD11c Hamster (Armenian) Monoclonal Antibody [clone: N418] (FITC)

Fournisseur: STEMCELL Technologies

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Fournisseur: STEMCELL Technologies

À propos de cet article

Hamster (Armenian) monoclonal IgG antibody against mouse CD11c, FITC-conjugated.

Dendritic cells

The N418 antibody reacts with CD11c (αX integrin), a 150 kDa type 1 transmembrane glycoprotein that associates non-covalently with CD18 (β2 integrin) to form a heterodimeric cell surface adhesion receptor. Through its interaction with ligands such as iC3b, fibrinogen, and CD54, the CD11c/CD18 receptor is involved in several immune response processes, including cell migration, stimulation of cytokine production by monocytes and macrophages, T cell proliferation, leukocyte recruitment, and phagocytosis. In mice, CD11c is expressed on dendritic cells, macrophages, monocytes, granulocytes, NK cells, and a subset of T cells. This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD11c Positive Selection Kit II (Catalog #18780).

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Type:
Antigen: CD11c
Clonality: Monoclonal
Clone: N418
Conjugation: FITC
Epitope:
Host: Hamster (Armenian)
Isotype: IgG
Reactivity: Mouse